ReviewJournal of clinical medicine2021
Dynamic Left Intraventricular Obstruction Phenotype in Takotsubo Syndrome.
Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 41 citations in OpenAlex.
- Mechanical circulatory support for cardiogenic shock in takotsubo syndrome.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Forward Dynamics: Modern Insights into Mitral Systolic Anterior Motion.Journal of cardiovascular development and disease · 2026Review
- Takotsubo syndrome complicated by dynamic left ventricular outflow tract obstruction after left bundle branch area pacing.HeartRhythm case reports · 2026Article
- Diagnostic Challenges in Takotsubo Syndrome: Bridging Mimics, Mechanisms, and Management.Journal of clinical medicine · 2026Review
- Presumed acute myocardial damage in a British Shorthair cat with previously diagnosed hypertrophic cardiomyopathy.Irish veterinary journal · 2026Article
- Vasopressin in cardiogenic shock: pathophysiology, clinical evidence, and therapeutic perspectives.ESC heart failure · 2026Article
- Brazilian Guideline for the Evaluation and Diagnosis of Chest Pain in the Emergency Department - 2025.Arquivos brasileiros de cardiologia · 2025Article
- Sigmoid Septum: A Bystander or Contributor to a Left Ventricular Outflow Tract Obstruction in Takotsubo Syndrome - A Case Report with a Literature Review.Internal medicine (Tokyo, Japan) · 2025Review
- Obesity Paradox in Takotsubo Syndrome Among Septic ICU Patients: A Retrospective Cohort Study.Journal of clinical medicine · 2025Article
- Cardiogenic shock in takotsubo syndrome: etiology and treatment.Cardiovascular intervention and therapeutics · 2024Review
- Acute Heart Failure in a Young Patient Treated in ICU-Diagnostic Pitfalls.Clinics and practice · 2024Article
- Perioperative management of Takotsubo cardiomyopathy: an overview.Journal of anesthesia, analgesia and critical care · 2024Review
- Takotsubo Cardiomyopathy: Patients Characteristics, Mortality, and Clinical Significance of Left Ventricular Outflow Tract Gradient, Retrospective Study.Cardiology research and practice · 2024Article
- Obstructive Hypertrophic Cardiomyopathy and Takotsubo Syndrome: How to Deal With Left Ventricular Ballooning?Journal of the American Heart Association · 2023Review
- Haemodynamic effects of acute intravenous landiolol in Takotsubo cardiomyopathy with dynamic left ventricular outflow tract obstruction.BMJ case reports · 2023Article
- Takotsubo Syndrome: From Bench to Bedside and Bedside to Bench.Journal of clinical medicine · 2022Article
- Takotsubo Syndrome: Translational Implications and Pathomechanisms.International journal of molecular sciences · 2022Review
- Coincidence of Events Causing Paradoxical Hypotension in a Patient with an Intra-Aortic Balloon Pump.European journal of case reports in internal medicine · 2022Article
- Acute Coronary Syndrome in Patients with SARS-CoV-2 Infection: Pathophysiology and Translational Perspectives.Translational medicine @ UniSa · 2022Article
- Transient Left Ventricular Outflow Tract Obstruction in an Elderly Patient Admitted with Takotsubo.Heart views : the official journal of the Gulf Heart AssociationArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Takotsubo syndrome (TTS) is characterized by acute, generally transient left ventricular (LV) dysfunction. Although TTS has been long regarded as a benign condition, recent evidence showed that rate of acute complications and in-hospital mortality is comparable to that of patients with acute coronary syndrome. In particular, the prevalence of cardiogenic shock ranges between 6% and 20%. In this setting, detection of mechanisms leading to cardiogenic shock can be challenging. Besides a severely impaired systolic function, onset of LV outflow tract obstruction (LVOTO) together with mitral regurgitation related to systolic anterior motion of mitral valve leaflets can lead to hemodynamic instability. Early identification of LVOTO with echocardiography is crucial and has important implications on selection of the appropriate therapy. Application of short-acting b1-selective betablockers and prudent administration of fluids might help to resolve LVOTO. Conversely, inotrope agents may increase basal hypercontractility and worsen the intraventricular pressure gradient. To date, outcomes and management of patients with TTS complicated by LVOTO as yet has not been comprehensively investigated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.