ArticleJournal of clinical medicine2021
Effect of Multimorbidity on Fragility Fractures in Community-Dwelling Older Adults: Shimane CoHRE Study.
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 19 citations in OpenAlex.
- Perioperative Bleeding Risk and Associated Factors in End-Stage Kidney Disease Patients Undergoing Intertrochanteric Fracture Surgery: Implications for Management.Orthopedic research and reviews · 2026Article
- Multimorbidity, fragility fractures, and out-of-pocket expenditure in older Indian adults: evidence from a national survey.Archives of osteoporosis · 2025Article
- Continuous Fascia Iliaca Compartment Block Improves Outcomes in Hip Fragility Fracture Patients.Cureus · 2025Article
- The associations of multimorbidity with fall- and fracture-related hospitalisations: the Busselton Healthy Ageing Study.Archives of osteoporosis · 2025Article
- Association between fractures and health status among independent older adults: insights from a suburban cohort in Japan.BMC geriatrics · 2025Article
- Examining the relationships between patients' multimorbidity trajectories and prognostic outcomes after the initial hip fracture.Scientific reports · 2024Article
- Multimorbidity patterns and the risk of falls among older adults: a community-based study in China.BMC geriatrics · 2024Article
- Chronic pain in older adults with disabilities is associated with fall-related injuries: a prospective cohort study.European geriatric medicine · 2024Article
- A genome-wide association study identifies a locus associated with knee extension strength in older Japanese individuals.Communications biology · 2024Article
- Health Perceptions, Multimorbidity, and New Fractures and Mortality Among Patients With a Fracture.JAMA network open · 2024Article
- Risk factors for osteoporotic hip fracture among community-dwelling older adults: a real-world evidence study.Advances in rheumatology (London, England) · 2024Article
- Article
- Low lymphocyte-to-C-reactive protein ratio relates to high 1-year mortality in elderly patients undergoing hemiarthroplasty for displaced femoral neck facture.Journal of orthopaedic surgery and research · 2022Article
- Multimorbidity and Polytherapy in Patients with Femoral Neck Fracture: A Retrospective Observational Study.Journal of clinical medicine · 2022Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fragility fractures (FFxs), which are a common musculoskeletal injury in older adults, is associated with an increased frequency of falls. Both FFxs and falls may result from drugs, habits, and co-occurring diseases. We aimed to evaluate the effects of various diseases on the risk of FFx. This retrospective study included 1420 individuals aged ≥60 years. We evaluated the history of clinical FFx and diseases using a detailed questionnaire and a health examination. The risk of comorbidities was assessed using the Age-Adjusted Charlson Comorbidity (AAC) Index. We performed binary logistic regression analysis to determine the risk of FFx and falls after adjusting for covariates. In elderly men, the incidence of FFx positively correlated with rheumatoid arthritis and parent's hip fracture. For elderly women, the incidence of FFx positively correlated with rheumatoid arthritis and antihypertensive drugs but was inversely associated with dyslipidemia and antilipidemic drugs. The FFX risk of older adults with an AAC Index ≥6 was higher than those with an AAC Index of 1-3. In addition, the AAC Index and falls were independently and strongly associated with a higher risk of FFx. Taken together, multimorbidity increases the risk of clinical FFx independent of falls in the community-dwelling elderly population.
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