Evidence map›Paper›PMID 34361984›Full record

ArticleJournal of clinical medicine2021

Clinical Relevance of a 16-Gene Pharmacogenetic Panel Test for Medication Management in a Cohort of 135 Patients.

David F Niedrig, Ali Rahmany, Kai Heib, Karl-Dietrich Hatz, Katja Ludin, Andrea M Burden, Markus Béchir, Andreas Serra, Stefan Russmann

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
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  10. The Implementation of Pharmacogenetics in the United Kingdom.Handbook of experimental pharmacology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

David F NiedrigDrugsafety.ch, 8703 Kusnacht, Switzerland.
Ali RahmanyDrugsafety.ch, 8703 Kusnacht, Switzerland.
Kai HeibINTLAB AG, 8707 Uetikon am See, Switzerland.ORCID 0000-0003-1020-435X
Karl-Dietrich HatzINTLAB AG, 8707 Uetikon am See, Switzerland.
Katja LudinLabor Risch, Molecular Genetics, 3097 Berne, Switzerland.
Andrea M BurdenSwiss Federal Institute of Technology Zurich (ETHZ), 8093 Zurich, Switzerland.ORCID 0000-0001-7082-8530
Markus BéchirCenter for Internal Medicine, Clinic Hirslanden Aarau, 5001 Aarau, Switzerland.
Andreas SerraInstitute of Internal Medicine and Nephrology, Clinic Hirslanden Zurich, 8032 Zurich, Switzerland.
Stefan RussmannDrugsafety.ch, 8703 Kusnacht, Switzerland.
Klinik Hirslanden · CHHirslanden Klinik Aarau · CHLabormedizinische Zentrum Dr Risch (Switzerland) · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a growing number of evidence-based indications for pharmacogenetic (PGx) testing. We aimed to evaluate clinical relevance of a 16-gene panel test for PGx-guided pharmacotherapy. In an observational cohort study, we included subjects tested with a PGx panel for variants of

Indexed as

clinical relevanceCYP450genetic panel testspharmacogeneticspharmacotherapySONOGEN XP

Identifiers

PMID34361984
PMCPMC8347064
OpenAlexW3152785448

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.