Evidence map›Paper›PMID 34361948›Full record

ReviewMicroorganisms2021

Probiotics in the Therapeutic Arsenal of Dermatologists.

Vicente Navarro-López, Eva Núñez-Delegido, Beatriz Ruzafa-Costas, Pedro Sánchez-Pellicer, Juan Agüera-Santos, Laura Navarro-Moratalla

Open access · goldAbstract readReview
In one paragraph

Review in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Oral Probiotics inMedicina (Kaunas, Lithuania) · 2025
    Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Skin Microbiome in Health and Disease: Mechanisms and Emerging Therapeutic Strategies.Clinical, cosmetic and investigational dermatology · 2025
    Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Vicente Navarro-LópezMiBioPath Research Group, Health and Science Faculty, Catholic University of Murcia, Campus de los Jerónimos n 135, 30107 Murcia, Spain.ORCID 0000-0003-3731-9827
Eva Núñez-DelegidoMiBioPath Research Group, Health and Science Faculty, Catholic University of Murcia, Campus de los Jerónimos n 135, 30107 Murcia, Spain.
Beatriz Ruzafa-CostasMiBioPath Research Group, Health and Science Faculty, Catholic University of Murcia, Campus de los Jerónimos n 135, 30107 Murcia, Spain.
Pedro Sánchez-PellicerMiBioPath Research Group, Health and Science Faculty, Catholic University of Murcia, Campus de los Jerónimos n 135, 30107 Murcia, Spain.
Juan Agüera-SantosMiBioPath Research Group, Health and Science Faculty, Catholic University of Murcia, Campus de los Jerónimos n 135, 30107 Murcia, Spain.
Laura Navarro-MoratallaMiBioPath Research Group, Health and Science Faculty, Catholic University of Murcia, Campus de los Jerónimos n 135, 30107 Murcia, Spain.
Universidad Católica de Murcia · ESHospital Universitario del Vinalopó · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the last years, numerous studies have described the presence of significant gut and skin dysbiosis in some dermatological diseases such as atopic dermatitis, psoriasis and acne, among others. How the skin and the gut microbiome play a role in those skin conditions is something to explore, which will shed light on understanding the origin and implication of the microbiota in their pathophysiology. Several studies provide evidence for the influence of probiotic treatments that target the modulation of the skin and intestinal microbiota in those disorders and a positive influence of orally administered probiotics on the course of these dermatosis. The pathologies in which the therapeutic role of the probiotic has been explored are mainly atopic dermatitis, psoriasis and acne. This article aims to review these three dermatological diseases, their relationship with the human microbiota and specially the effect of probiotics usage. In addition, the pathophysiology in each of them and the hypotheses about possible mechanisms of the action of probiotics will be described.

Indexed as

acneatopic dermatitisgut dysbiosismicrobiotaprobioticpsoriasisskin microbiome

Identifiers

PMID34361948
PMCPMC8303240
OpenAlexW3181240461

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.