Evidence map›Paper›PMID 34361750›Full record

ArticleMolecules (Basel, Switzerland)2021

Betulin, a Newly Characterized Compound in

Augustine A Ahmadu, Claire Delehouzé, Anas Haruna, Lukman Mustapha, Bilqis A Lawal, Aniefiok Udobre, Blandine Baratte, Camilla Triscornia, Axelle Autret, Thomas Robert and 7 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 4 countries.

Augustine A AhmaduDepartment of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmaceutical Sciences, Kaduna State University, Kaduna 800241, Nigeria.
Claire DelehouzéStation Biologique de Roscoff, CNRS, UMR8227, Integrative Biology of Marine Models Laboratory (LBI2M), Sorbonne Université, 29680 Roscoff, France.
Anas HarunaDepartment of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmaceutical Sciences, Kaduna State University, Kaduna 800241, Nigeria.ORCID 0000-0003-3820-7886
Lukman MustaphaDepartment of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmaceutical Sciences, Kaduna State University, Kaduna 800241, Nigeria.
Bilqis A LawalDepartment of Pharmacognosy and Drug Development, Faculty of Pharmaceutical Sciences, University of Ilorin, Ilorin 240003, Nigeria.
Aniefiok UdobreDepartment of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmacy, University of Uyo, Uyo 520003, Nigeria.
Blandine BaratteStation Biologique de Roscoff, CNRS, UMR8227, Integrative Biology of Marine Models Laboratory (LBI2M), Sorbonne Université, 29680 Roscoff, France.ORCID 0000-0002-2064-9558
Camilla TriscorniaStation Biologique de Roscoff, CNRS, UMR8227, Integrative Biology of Marine Models Laboratory (LBI2M), Sorbonne Université, 29680 Roscoff, France.
Axelle AutretPlace Georges Teissier, SeaBeLife Biotech, 29680 Roscoff, France.
Thomas RobertStation Biologique de Roscoff, CNRS, UMR8227, Integrative Biology of Marine Models Laboratory (LBI2M), Sorbonne Université, 29680 Roscoff, France.
Jeannette Chloë BulinskiStation Biologique de Roscoff, CNRS, UMR8227, Integrative Biology of Marine Models Laboratory (LBI2M), Sorbonne Université, 29680 Roscoff, France.
Morgane RousselotPlace Georges Teissier, SeaBeLife Biotech, 29680 Roscoff, France.
Mélanie Simoes EugénioPlace Georges Teissier, SeaBeLife Biotech, 29680 Roscoff, France.ORCID 0000-0001-6776-4839
Marie-Thérèse Dimanche-BoitrelInstitut de Recherche sur la Santé, l'Environnement et le Travail (IRSET), INSERM UMR 1085, F-35043 Rennes, France.
Jacobus P PetzerCentre of Excellence for Pharmaceutical Sciences, North-West University, Private Bag X6001, Potchefstroom 2520, South Africa.ORCID 0000-0002-7114-8120
Lesetja J LegoabeCentre of Excellence for Pharmaceutical Sciences, North-West University, Private Bag X6001, Potchefstroom 2520, South Africa.ORCID 0000-0003-2440-4993
Stéphane BachStation Biologique de Roscoff, CNRS, UMR8227, Integrative Biology of Marine Models Laboratory (LBI2M), Sorbonne Université, 29680 Roscoff, France.ORCID 0000-0002-7186-7483
Centre National de la Recherche Scientifique · FRKaduna State University · NGInserm · FRNorth-West University · ZAStation Biologique de Roscoff · FRUniversity of Ilorin · NGUniversity of Uyo · NG

Funding

Agence Nationale de la Recherche Investissements d'Avenir program via the OCEANOMICs project, grant #ANR-11-BTBR-0008Association Nationale de la Recherche et de la Technologie Cifre#2019/0686Fondation d'Entreprise Grand Ouest (BPGO) HouarnineTertiary Education Trust Fund TETFund/Sep2018
6 · The paper itself

Abstract

The purpose of this work is to investigate the protein kinase inhibitory activity of constituents from

Indexed as

AcaciaAntineoplastic Agents, PhytogenicApoptosisBetulinic AcidBinding SitesCasein Kinase 1 epsilonCell ProliferationFusion Proteins, bcr-ablGene Expression Regulation, LeukemicGlycogen Synthase Kinase 3HumansJanus Kinase 3K562 CellsMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3Models, MolecularABL1 protein, humanAntineoplastic Agents, PhytogenicBCR-ABL1 fusion protein, humanbetulinBetulinic AcidCasein Kinase 1 epsilonFusion Proteins, bcr-ablGlycogen Synthase Kinase 3glycogen synthase kinase 3 alphaJAK3 protein, humanJanus Kinase 3KDR protein, humanMAPK1 protein, humanMAPK3 protein, humanMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3NEK6 protein, humanNIMA-Related KinasesPlant ExtractsProtein Kinase InhibitorsProto-Oncogene Proteins c-ablTriterpenesVascular Endothelial Growth Factor Receptor-2Acacia stem barkpolypharmacologyprotein kinase inhibitorstriterpenoids

Identifiers

PMID34361750
PMCPMC8347092
OpenAlexW3169515987

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.