Evidence map›Paper›PMID 34361745›Full record

ArticleMolecules (Basel, Switzerland)2021

Assessment of Chemopreventive Potential of the Plant Extracts against Liver Cancer Using HepG2 Cell Line.

Deepthi Venkatachalapathy, Chandan Shivamallu, Shashanka K Prasad, Gopenath Thangaraj Saradha, Parthiban Rudrapathy, Raghavendra G Amachawadi, Sharanagouda S Patil, Asad Syed, Abdallah M Elgorban, Ali H Bahkali and 2 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 27 citations in OpenAlex.

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  7. Unraveling the Bioactive Potential ofPharmaceuticals (Basel, Switzerland) · 2024
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  8. Evidence-based complementary and alternative medicine : eCAM · 2023
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  10. Heartwood Extract ofMetabolites · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 3 countries.

Deepthi VenkatachalapathyDivision of Molecular Biology, Faculty of Life Science, JSS Academy of Higher Education & Research, Mysuru 570015, India.
Chandan ShivamalluDepartment of Biotechnology and Bioinformatics, School of Life Sciences, JSS Academy of Higher Education and Research, Mysuru 570105, India.ORCID 0000-0002-1886-139X
Shashanka K PrasadDepartment of Biotechnology and Bioinformatics, School of Life Sciences, JSS Academy of Higher Education and Research, Mysuru 570105, India.ORCID 0000-0002-1519-5205
Gopenath Thangaraj SaradhaDepartment of Biotechnology and Bioinformatics, School of Life Sciences, JSS Academy of Higher Education and Research, Mysuru 570105, India.
Parthiban RudrapathyMalabar Cancer Centre, Department of Clinical Laboratory Services & Translational Research, Thalassery, Kannur 670103, India.ORCID 0000-0002-1200-5111
Raghavendra G AmachawadiDepartment of Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506-5606, USA.ORCID 0000-0001-9689-1124
Sharanagouda S PatilICAR, National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Yelahanka, Bengaluru 560064, India.ORCID 0000-0002-3291-7513
Asad SyedDepartment of Botany and Microbiology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Abdallah M ElgorbanDepartment of Botany and Microbiology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.ORCID 0000-0003-3664-7853
Ali H BahkaliDepartment of Botany and Microbiology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Shiva Prasad KollurDepartment of Sciences, Amrita School of Arts and Sciences, Amrita Vishwa Vidyapeetham, Mysuru Campus, Mysuru 570026, India.ORCID 0000-0003-3914-3933
Kanthesh M BasalingappaDivision of Molecular Biology, Faculty of Life Science, JSS Academy of Higher Education & Research, Mysuru 570015, India.ORCID 0000-0002-6970-4546
JSS Academy of Higher Education and Research · INKing Saud University · SAAmrita Vishwa Vidyapeetham · INKansas State University · USMalabar Cancer Centre · INNational Institute Of Veterinary Epidemiology And Disease Informatics · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The edible parts of the plants

Indexed as

Alkaloidsalpha-AmylasesAntineoplastic Agents, PhytogenicAntioxidantsbcl-2-Associated X ProteinBiphenyl CompoundsCamellia sinensisCell DeathFlavonoidsGene Expression Regulation, NeoplasticHep G2 CellsHumansPicratesPlant ExtractsPlant LeavesProto-Oncogene Proteins c-bcl-21,1-diphenyl-2-picrylhydrazylAlkaloidsalpha-AmylasesAntineoplastic Agents, PhytogenicAntioxidantsBAX protein, humanbcl-2-Associated X ProteinBCL2 protein, humanBiphenyl CompoundsFlavonoidsPicratesPlant ExtractsProto-Oncogene Proteins c-bcl-2TanninsTerpenesanti-carcinogenicantioxidantsCamellia sinensisHepG2 cell lineVitis viniferaWithania somnifera

Identifiers

PMID34361745
PMCPMC8348645
OpenAlexW3184504211

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.