Evidence map›Paper›PMID 34361622›Full record

ArticleMolecules (Basel, Switzerland)2021

Antiproliferative Effect of Colonic Fermented Phenolic Compounds from Jaboticaba (

Paula Rossini Augusti, Andréia Quatrin, Renius Mello, Vivian Caetano Bochi, Eliseu Rodrigues, Inês D Prazeres, Ana Catarina Macedo, Sheila Cristina Oliveira-Alves, Tatiana Emanuelli, Maria Rosário Bronze and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Review
  3. Plants (Basel, Switzerland) · 2024
    Article
  4. Redox Active Molecules in Cancer Treatments.Molecules (Basel, Switzerland) · 2023
    Article
  5. Article
  6. Therapeutic approaches to colorectal cancerFrontiers in microbiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Paula Rossini AugustiDepartamento de Ciências dos Alimentos, Instituto de Ciência e Tecnologia de Alimentos (ICTA), Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre 91501-970, Brazil.
Andréia QuatrinNúcleo Integrado de Desenvolvimento em Análises Laboratoriais (NIDAL), Centro de Ciências Rurais, Departamento de Tecnologia e Ciência dos Alimentos, Universidade Federal de Santa Maria, Santa Maria 97105-900, Brazil.
Renius MelloNúcleo Integrado de Desenvolvimento em Análises Laboratoriais (NIDAL), Centro de Ciências Rurais, Departamento de Tecnologia e Ciência dos Alimentos, Universidade Federal de Santa Maria, Santa Maria 97105-900, Brazil.ORCID 0000-0002-5934-7784
Vivian Caetano BochiDepartamento de Nutrição, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre 91501-970, Brazil.
Eliseu RodriguesDepartamento de Ciências dos Alimentos, Instituto de Ciência e Tecnologia de Alimentos (ICTA), Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre 91501-970, Brazil.
Inês D PrazeresiBET, Instituto de Biologia Experimental e Tecnológica, Apartado 12, 2780-901 Oeiras, Portugal.
Ana Catarina MacedoiBET, Instituto de Biologia Experimental e Tecnológica, Apartado 12, 2780-901 Oeiras, Portugal.
Sheila Cristina Oliveira-AlvesiBET, Instituto de Biologia Experimental e Tecnológica, Apartado 12, 2780-901 Oeiras, Portugal.
Tatiana EmanuelliNúcleo Integrado de Desenvolvimento em Análises Laboratoriais (NIDAL), Centro de Ciências Rurais, Departamento de Tecnologia e Ciência dos Alimentos, Universidade Federal de Santa Maria, Santa Maria 97105-900, Brazil.ORCID 0000-0003-0168-3416
Maria Rosário BronzeiBET, Instituto de Biologia Experimental e Tecnológica, Apartado 12, 2780-901 Oeiras, Portugal.ORCID 0000-0001-5016-4634
Ana Teresa SerraiBET, Instituto de Biologia Experimental e Tecnológica, Apartado 12, 2780-901 Oeiras, Portugal.ORCID 0000-0002-8618-8299
Instituto de Biologia Experimental e Tecnológica · PTUniversidade Federal de Santa Maria · BRUniversidade Federal do Rio Grande do Sul · BRUniversidade Federal de Ciências da Saúde de Porto Alegre · BRUniversity of Lisbon · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Jaboticaba is a Brazilian native berry described as a rich source of phenolic compounds (PC) with health promoting effects. PC from jaboticaba peel powder (JPP) have low intestinal bio-accessibility and are catabolized by gut microbiota. However, the biological implication of PC-derived metabolites produced during JPP digestion remains unclear. This study aimed to evaluate the antiproliferative effects of colonic fermented JPP (FJPP) in a 3D model of colorectal cancer (CRC) composed by HT29 spheroids. JPP samples fermented with human feces during 0, 2, 8, 24 or 48 h were incubated (10,000 µg mL

Indexed as

Antineoplastic AgentsAntioxidantsCaco-2 CellsCell ProliferationCell SurvivalColorectal NeoplasmsHT29 CellsHumansMyrtaceaePhenolsPlant ExtractsAntineoplastic AgentsAntioxidantsPhenolsPlant Extractscluster analysisdihydroxyphenyl-γ-valerolactoneHHDP-digalloylglucose isomerHT29 cellshydrolysable tanninsprincipal component analysisspheroids

Identifiers

PMID34361622
PMCPMC8347777
OpenAlexW3186627593

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.