Evidence map›Paper›PMID 34361494›Full record

ArticleMaterials (Basel, Switzerland)2021

Scanning Electrochemical Impedance Microscopy in Redox-Competition Mode for the Investigation of Antibodies Labelled with Horseradish Peroxidase.

Antanas Zinovicius, Inga Morkvenaite-Vilkonciene, Almira Ramanaviciene, Juste Rozene, Anton Popov, Arunas Ramanavicius

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Scanning Electrochemical Impedance Microscopy-Based Assessment of Glucose Biosensors.Langmuir : the ACS journal of surfaces and colloids · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Antanas ZinoviciusDepartment of Mechatronics and Robotics, Vilnius Gediminas Technical University, J. Basanavičiaus 28, LT-03224 Vilnius, Lithuania.ORCID 0000-0003-0865-5880
Inga Morkvenaite-VilkoncieneDepartment of Mechatronics and Robotics, Vilnius Gediminas Technical University, J. Basanavičiaus 28, LT-03224 Vilnius, Lithuania.
Almira RamanavicieneNanoTechnas-Center of Nanotechnology and Materials Science, Faculty of Chemistry and Geosciences, Vilnius University, Naugarduko 24, LT-03225 Vilnius, Lithuania.ORCID 0000-0002-0885-3556
Juste RozeneDepartment of Mechatronics and Robotics, Vilnius Gediminas Technical University, J. Basanavičiaus 28, LT-03224 Vilnius, Lithuania.ORCID 0000-0002-4741-7888
Anton PopovNanoTechnas-Center of Nanotechnology and Materials Science, Faculty of Chemistry and Geosciences, Vilnius University, Naugarduko 24, LT-03225 Vilnius, Lithuania.ORCID 0000-0002-9867-1931
Arunas RamanaviciusDepartment of Physical Chemistry, Institute of Chemistry, Faculty of Chemistry and Geosciences, Vilnius University, Naugarduko 24, LT-03225 Vilnius, Lithuania.ORCID 0000-0001-5864-0359
Vilnius Gediminas Technical University · LTVilnius University · LT

Funding

European Social Fund 09.3.3-LMT-K-712-233 02-0137
6 · The paper itself

Abstract

Scanning electrochemical microscopy enhanced by electrochemical impedance spectroscopy (SEIM) was applied to detect immobilized antibodies labelled with horseradish peroxidase (Ab-HRP). The localized HRP activity was investigated by the SEIM redox competition (RC-SEIM) mode using hydrogen peroxide as a substrate and hexacyanoferrate as a redox mediator. Electrochemical impedance shows to be related to the consumption of hydrogen peroxide at the ultramicroelectrode. For the evaluation of impedimetric results, an equivalent electric circuit was applied with solution resistance, double-layer capacitance, and charge-transfer resistance. These equivalent circuit characteristics depend on the distance between the sample and ultramicroelectrode, and the concentration of substrate. From the gathered data, the charge-transfer resistance appeared to be the parameter describing the behavior of HRP catalyzed reaction as it showed a linear dependence on H

Indexed as

antigen-antibody complexbioelectrochemistrybioelectronicselectrochemical impedance spectroscopyelectrochemical methodshorseradish peroxidaseimmunoassayscanning electrochemical impedance microscopyscanning electrochemical microscopyultra-micro electrode

Identifiers

PMID34361494
PMCPMC8348749
OpenAlexW3191945100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.