Evidence map›Paper›PMID 34361251›Full record

ReviewNanomaterials (Basel, Switzerland)2021

Multifunctional Gold Nanorod for Therapeutic Applications and Pharmaceutical Delivery Considering Cellular Metabolic Responses, Oxidative Stress and Cellular Longevity.

Seyyed Mojtaba Mousavi, Seyyed Alireza Hashemi, Sargol Mazraedoost, Khadije Yousefi, Ahmad Gholami, Gity Behbudi, Seeram Ramakrishna, Navid Omidifar, Ali Alizadeh, Wei-Hung Chiang

Abstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  5. Bornite (CuPhotoacoustics · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Seyyed Mojtaba MousaviDepartment of Chemical Engineering, National Taiwan University of Science and Technology, Taipei 10617, Taiwan.
Seyyed Alireza HashemiNanomaterials and Polymer Nanocomposites Laboratory, School of Engineering, University of British Columbia, Kelowna, BC V1V 1V7, Canada.ORCID 0000-0002-4713-6883
Sargol MazraedoostBiotechnology Research Center, Shiraz University of Medical Sciences, Shiraz 71345-1583, Iran.ORCID 0000-0001-6656-1968
Khadije YousefiBiotechnology Research Center, Shiraz University of Medical Sciences, Shiraz 71345-1583, Iran.
Ahmad GholamiBiotechnology Research Center, Shiraz University of Medical Sciences, Shiraz 71345-1583, Iran.ORCID 0000-0003-1851-159X
Gity BehbudiDepartment of Chemical Engineering, University of Mohaghegh Ardabili, Ardabil 56199-11367, Iran.
Seeram RamakrishnaDepartment of Mechanical Engineering, Center for Nanofibers and Nanotechnology, National University of Singapore, Singapore 117581, Singapore.ORCID 0000-0001-8479-8686
Navid OmidifarBiotechnology Research Center, Shiraz University of Medical Sciences, Shiraz 71345-1583, Iran.ORCID 0000-0003-3391-926X
Ali AlizadehNanobiology and Nanomedicine Research Center, Shiraz University of Medical Sciences, Shiraz 71345-1583, Iran.
Wei-Hung ChiangDepartment of Chemical Engineering, National Taiwan University of Science and Technology, Taipei 10617, Taiwan.ORCID 0000-0002-6350-6696

Funding

Mininstry of science and technology of Taiwan 109-NU-E-011-001-NU
6 · The paper itself

Abstract

Multifunctional gold nanorods (GNR) have drawn growing interest in biomedical fields because of their excellent biocompatibility, ease of alteration, and special optical properties. The great advantage of using GNR in medicine is their application to Photothermal therapy (PPTT), which is possible thanks to their ability to turn luminous energy into heat to cause cellular hyperthermia. For this purpose, the relevant articles between 1988 and 2020 were searched in databases such as John Wiley, Free paper, Scopus, Science Direct, and Springer to obtain the latest findings on multifunctional gold nanorods for therapeutic applications and pharmaceutical delivery. In this article, we review recent progress in diagnostic and therapeutic applications of multifunctional GNR, highlighting new information about their toxicity to various cellular categories, oxidative stress, cellular longevity, and their metabolic effects, such as the effect on the energy cycles and genetic structures. The methods for the synthesis and functionalization of GNR were surveyed. This review includes new information about GNR toxicity to various cellular categories and their metabolic effects.

Indexed as

cellular longevitycellular metabolic responsesmultifunctional gold nanorodsoxidative stresstherapeutic applications

Identifiers

PMID34361251
PMCPMC8308363

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.