Evidence map›Paper›PMID 34361080›Full record

ArticleInternational journal of molecular sciences2021

Quantitative Radionuclide Imaging Analysis of Enhanced Drug Delivery Induced by Photoimmunotherapy.

Winn Aung, Atsushi B Tsuji, Aya Sugyo, Masayuki Fujinaga, Ming-Rong Zhang, Tatsuya Higashi

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Winn AungDepartment of Molecular Imaging and Theranostics, Institute for Quantum Medical Science, National Institutes for Quantum and Radiological Science and Technology (QST-iQMS), Inage, Chiba 263-8555, Japan.ORCID 0000-0002-0896-7158
Atsushi B TsujiDepartment of Molecular Imaging and Theranostics, Institute for Quantum Medical Science, National Institutes for Quantum and Radiological Science and Technology (QST-iQMS), Inage, Chiba 263-8555, Japan.ORCID 0000-0003-2726-288X
Aya SugyoDepartment of Molecular Imaging and Theranostics, Institute for Quantum Medical Science, National Institutes for Quantum and Radiological Science and Technology (QST-iQMS), Inage, Chiba 263-8555, Japan.ORCID 0000-0002-5174-4478
Masayuki FujinagaDepartment of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Science, National Institutes for Quantum and Radiological Science and Technology (QST-iQMS), Inage, Chiba 263-8555, Japan.
Ming-Rong ZhangDepartment of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Science, National Institutes for Quantum and Radiological Science and Technology (QST-iQMS), Inage, Chiba 263-8555, Japan.
Tatsuya HigashiDepartment of Molecular Imaging and Theranostics, Institute for Quantum Medical Science, National Institutes for Quantum and Radiological Science and Technology (QST-iQMS), Inage, Chiba 263-8555, Japan.
National Institutes for Quantum Science and Technology · JP

Funding

Japan Society for the Promotion of Science 17K10460Japan Society for the Promotion of Science 21K07740
6 · The paper itself

Abstract

Photoimmunotherapy (PIT) is an upcoming potential cancer treatment modality, the effect of which is improved in combination with chemotherapy. PIT causes a super-enhanced permeability and retention (SUPR) effect. Here, we quantitatively evaluated the SUPR effect using radiolabeled drugs of varying molecular weights (

Indexed as

Drug Delivery SystemsAnimalsAntibodies, MonoclonalApoptosisCell ProliferationCombined Modality TherapyHumansImmunotherapyIndocyanine GreenMaleMiceMice, Inbred BALB CMice, NudeNeoplasmsPhototherapyRadionuclide ImagingAntibodies, MonoclonalIndocyanine Greenindocyanine greenphotoimmunotherapy (PIT)positron emission tomography (PET)radionuclide imagingsingle-photon emission computed tomography (SPECT)super-enhanced permeability and retention (SUPR)

Identifiers

PMID34361080
PMCPMC8348642
OpenAlexW3192107815

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.