Evidence map›Paper›PMID 34361042›Full record

ArticleInternational journal of molecular sciences2021

Loss of

Pavel A Melentev, Elena V Ryabova, Nina V Surina, Darya R Zhmujdina, Artem E Komissarov, Ekaterina A Ivanova, Natalia P Boltneva, Galina F Makhaeva, Mariana I Sliusarenko, Andriy S Yatsenko and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 18 citations in OpenAlex.

  1. Fly · 2026
    Review
  2. Review
  3. Article
  4. International journal of molecular sciences · 2026
    Article
  5. Article
  6. Review
  7. The cyclic nucleotide binding sites of Swiss-Cheese, thebioRxiv : the preprint server for biology · 2025
    Article
  8. Article
  9. International journal of molecular sciences · 2025
    Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. PNPLA6-Related Disorder with Levodopa-Responsive Parkinsonism.Movement disorders clinical practice · 2023
    Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Insects · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Pavel A MelentevPetersburg Nuclear Physics Institute Named by B.P. Konstantinov of NRC «Kurchatov Institute», 188300 Gatchina, Russia.ORCID 0000-0002-0620-4747
Elena V RyabovaPetersburg Nuclear Physics Institute Named by B.P. Konstantinov of NRC «Kurchatov Institute», 188300 Gatchina, Russia.ORCID 0000-0003-0813-6722
Nina V SurinaPetersburg Nuclear Physics Institute Named by B.P. Konstantinov of NRC «Kurchatov Institute», 188300 Gatchina, Russia.ORCID 0000-0002-7863-1748
Darya R ZhmujdinaPetersburg Nuclear Physics Institute Named by B.P. Konstantinov of NRC «Kurchatov Institute», 188300 Gatchina, Russia.
Artem E KomissarovPetersburg Nuclear Physics Institute Named by B.P. Konstantinov of NRC «Kurchatov Institute», 188300 Gatchina, Russia.ORCID 0000-0002-3564-1698
Ekaterina A IvanovaPetersburg Nuclear Physics Institute Named by B.P. Konstantinov of NRC «Kurchatov Institute», 188300 Gatchina, Russia.
Natalia P BoltnevaInstitute of Physiologically Active Compounds Russian Academy of Sciences, 142432 Chernogolovka, Russia.ORCID 0000-0002-7171-8832
Galina F MakhaevaInstitute of Physiologically Active Compounds Russian Academy of Sciences, 142432 Chernogolovka, Russia.ORCID 0000-0002-8136-6906
Mariana I SliusarenkoInstitute of Cell Biochemistry, Hannover Medical School, 30625 Hannover, Germany.
Andriy S YatsenkoInstitute of Cell Biochemistry, Hannover Medical School, 30625 Hannover, Germany.
Iryna I MohylyakDepartment of Genetics and Biotechnology, Ivan Franko National University of Lviv, 79005 Lviv, Ukraine.
Nataliya P MatiytsivDepartment of Genetics and Biotechnology, Ivan Franko National University of Lviv, 79005 Lviv, Ukraine.ORCID 0000-0002-1582-2037
Halyna R ShcherbataInstitute of Cell Biochemistry, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0002-3855-0345
Svetlana V SarantsevaPetersburg Nuclear Physics Institute Named by B.P. Konstantinov of NRC «Kurchatov Institute», 188300 Gatchina, Russia.
Petersburg Nuclear Physics Institute · RUMedizinische Hochschule Hannover · DEInstitute of Physiologically Active Compounds · RULviv University · UA

Funding

IPAC RAS State Targets Project 0090-2019-0005Russian Foundation for Basic Research 20-34-90148Volkswagen Stiftung 90218 and 97750
6 · The paper itself

Abstract

Various neurodegenerative disorders are associated with human NTE/PNPLA6 dysfunction. Mechanisms of neuropathogenesis in these diseases are far from clearly elucidated. Hereditary spastic paraplegia belongs to a type of neurodegeneration associated with NTE/PNLPLA6 and is implicated in neuron death. In this study, we used

Indexed as

AnimalsBrainDrosophila melanogasterDrosophila ProteinsLipid DropletsLipid MetabolismMitochondriaNerve Tissue ProteinsNeuronsOxidative StressReactive Oxygen SpeciesDrosophila ProteinsNerve Tissue ProteinsReactive Oxygen SpeciesSWS protein, DrosophilaDrosophila melanogasterhereditary spastic paraplegialipid dropletsmitochondrianeurodegenerationNTEoxidative stressPNPLA6ROSswiss cheese

Identifiers

PMID34361042
PMCPMC8347196
OpenAlexW3192589183

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.