Evidence map›Paper›PMID 34361029›Full record

ArticleInternational journal of molecular sciences2021

Identification of Spiro-Fused [3-azabicyclo[3.1.0]hexane]oxindoles as Potential Antitumor Agents: Initial In Vitro Evaluation of Anti-Proliferative Effect and Actin Cytoskeleton Transformation in 3T3 and 3T3-SV40 Fibroblast.

Nickolay A Knyazev, Stanislav V Shmakov, Sofya A Pechkovskaya, Alexander S Filatov, Alexander V Stepakov, Vitali M Boitsov, Natalia A Filatova

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Study of Cytotoxicity of 3-Azabicyclo[3.1.0]hexanes and Cyclopropa[International journal of molecular sciences · 2025
    Article
  4. Article
  5. 11International journal of molecular sciences · 2022
    Article
  6. Article
  7. Identification of Spiro-Fused Pyrrolo[3,4-International journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Nickolay A KnyazevSaint-Petersburg Clinical Scientific and Practical Center for Specialized Types of Medical Care (Oncological), 197758 Saint Petersburg, Russia.
Stanislav V ShmakovSaint Petersburg National Research Academic University of the Russian Academy of Sciences, 194021 Saint Petersburg, Russia.
Sofya A PechkovskayaInstitute of Cytology, Russian Academy of Sciences, 194064 Saint Petersburg, Russia.
Alexander S FilatovDepartment of Chemistry, Saint Petersburg State University, 199034 Saint Petersburg, Russia.
Alexander V StepakovDepartment of Chemistry, Saint Petersburg State University, 199034 Saint Petersburg, Russia.
Vitali M BoitsovSaint Petersburg National Research Academic University of the Russian Academy of Sciences, 194021 Saint Petersburg, Russia.ORCID 0000-0002-4857-2046
Natalia A FilatovaInstitute of Cytology, Russian Academy of Sciences, 194064 Saint Petersburg, Russia.
Institute of Cytology · RUSaint Petersburg Academic University · RUSt Petersburg University · RU

Funding

Russian Science Foundation 20-15-00332
6 · The paper itself

Abstract

Novel heterocyclic compounds containing 3-spiro[3-azabicyclo[3.1.0]hexane]oxindole framework (

Indexed as

3T3 CellsActin CytoskeletonAnimalsAntineoplastic AgentsCell ProliferationHumansK562 CellsMiceOxindolesPyrrolidinesAntineoplastic AgentsOxindolesPyrrolidines3-spiro[azabicyclo[3.1.0]hexane]oxindoles3T33T3-SV40actinADMET analysiscell cyclecytoskeletonmetastasistumor cells

Identifiers

PMID34361029
PMCPMC8347490
OpenAlexW3188623732

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.