Evidence map›Paper›PMID 34361007›Full record

ReviewInternational journal of molecular sciences2021

Mechanisms of Immunotoxicity: Stressors and Evaluators.

Maroun Bou Zerdan, Sara Moussa, Ali Atoui, Hazem I Assi

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. AI/ML-based computational models for toxicity prediction.Environmental science and pollution research international · 2026
    Review
  2. Article
  3. Phytochemicals fromFoods (Basel, Switzerland) · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. ACS omega · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Identification of key genes and molecular mechanisms of chronic urticaria based on bioinformatics.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
  14. RSC advances · 2024
    Article
  15. Review
  16. Review
  17. Climate Stressors and Physiological Dysregulations: Mechanistic Connections to Pathologies.International journal of environmental research and public health · 2023
    Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Maroun Bou ZerdanDepartment of Internal Medicine, Naef K. Basile Cancer Institute, American University of Beirut Medical Center, 1107 2020 Beirut, Lebanon.ORCID 0000-0002-9229-3079
Sara MoussaFaculty of Medicine, University of Balamand, 1100 Beirut, Lebanon.
Ali AtouiDepartment of Internal Medicine, Naef K. Basile Cancer Institute, American University of Beirut Medical Center, 1107 2020 Beirut, Lebanon.
Hazem I AssiDepartment of Internal Medicine, Naef K. Basile Cancer Institute, American University of Beirut Medical Center, 1107 2020 Beirut, Lebanon.ORCID 0000-0002-8483-0938

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The immune system defends the body against certain tumor cells and against foreign agents such as fungi, parasites, bacteria, and viruses. One of its main roles is to distinguish endogenous components from non-self-components. An unproperly functioning immune system is prone to primary immune deficiencies caused by either primary immune deficiencies such as genetic defects or secondary immune deficiencies such as physical, chemical, and in some instances, psychological stressors. In the manuscript, we will provide a brief overview of the immune system and immunotoxicology. We will also describe the biochemical mechanisms of immunotoxicants and how to evaluate immunotoxicity.

Indexed as

AllergensAnimalsEnvironmental IllnessFood HypersensitivityHumansIntestinal MucosaRespiratory HypersensitivityRespiratory MucosaAllergensallergieschemicalscigarette smokehypersensitivitiesimmune systemimmunotoxicitymicrobiotastressors

Identifiers

PMID34361007
PMCPMC8348050

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.