Evidence map›Paper›PMID 34360981›Full record

ArticleInternational journal of molecular sciences2021

Reduced Endothelin-2 and Hypoxic Signaling Pathways in Granulosa-Lutein Cells of PCOS Women.

Magdalena Szymanska, Ketan Shrestha, Eliezer Girsh, Avi Harlev, Iris Eisenberg, Tal Imbar, Rina Meidan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Endothelin 2: a key player in ovulation and fertility.Reproduction (Cambridge, England) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Magdalena SzymanskaDepartment of Animal Sciences, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot 7610001, Israel.ORCID 0000-0002-7159-2256
Ketan ShresthaDepartment of Animal Sciences, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot 7610001, Israel.
Eliezer GirshFertility and IVF Unit, Barzilai University Medical Center, Ashkelon 7830604, Israel.
Avi HarlevFertility and IVF Unit, Barzilai University Medical Center, Ashkelon 7830604, Israel.
Iris EisenbergThe Magda and Richard Hoffman Center for Human Placenta Research, Department of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, Jerusalem 91240, Israel.
Tal ImbarThe Magda and Richard Hoffman Center for Human Placenta Research, Department of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, Jerusalem 91240, Israel.ORCID 0000-0002-8583-1596
Rina MeidanDepartment of Animal Sciences, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot 7610001, Israel.ORCID 0000-0002-6727-6787
Hebrew University of Jerusalem · ILBarzilai Medical Center · ILBen-Gurion University of the Negev · ILHadassah Medical Center · ILUniversity of Kentucky · US

Funding

e German-Israeli Foundation for Scientific Research 379 and Development (GIF) I-1417the Robert H. Smith Faculty of Agriculture, Food and Environment Research Fund for International Cooperation scholarship N/A
6 · The paper itself

Abstract

Granulosa-lutein cells (GLCs) from PCOS women display reduced

Indexed as

Signal TransductionAdultCells, CulturedEndothelin-2FemaleGranulosa CellsHumansHypoxia-Inducible Factor 1, alpha SubunitLuteal CellsMicroRNAsPolycystic Ovary SyndromeVascular Endothelial Growth Factor AEndothelin-2HIF1A protein, humanHypoxia-Inducible Factor 1, alpha SubunitMicroRNAsMIRN210 microRNA, humanVascular Endothelial Growth Factor AVEGFA protein, humancorpus luteumHIF-1αmiR-210ovulationVEGFA

Identifiers

PMID34360981
PMCPMC8347025
OpenAlexW3191033194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.