Evidence map›Paper›PMID 34360946›Full record

ReviewInternational journal of molecular sciences2021

Mitochondrial Dynamics and Mitophagy in Skeletal Muscle Health and Aging.

Jean-Philippe Leduc-Gaudet, Sabah N A Hussain, Esther Barreiro, Gilles Gouspillou

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 162 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
162citing papers in PubMed, 1 pooled it
18.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

162 citing papers in PubMed, 1 synthesis or guideline pooled it, 232 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. The two faces of mitochondrial CaJournal of physiology and biochemistry · 2026
    Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Cellular Senescence in Skeletal Muscle Aging.Endocrinology and metabolism (Seoul, Korea) · 2026
    Review
  20. Article

102 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Jean-Philippe Leduc-GaudetResearch Institute of the McGill University Health Centre, Department of Critical Care, Montréal, QC H4A 3J1, Canada.ORCID 0000-0002-7637-5445
Sabah N A HussainResearch Institute of the McGill University Health Centre, Department of Critical Care, Montréal, QC H4A 3J1, Canada.
Esther BarreiroPulmonology Department-Muscle Wasting & Cachexia in Chronic Respiratory Diseases & Lung Cancer Research Group, IMIM-Hospital del Mar, Parc de Salut Mar, Biomedical Research Park (PRBB), C/Dr. Aiguader, 88, 08003 Barcelona, Spain.
Gilles GouspillouResearch Institute of the McGill University Health Centre, Department of Critical Care, Montréal, QC H4A 3J1, Canada.ORCID 0000-0002-8543-3619
Université du Québec à Montréal · CAMcGill University Health Centre · CAUniversitat Pompeu Fabra · ES

Funding

CIHR MOP-93760CIHR MOV-409262Natural Sciences and Engineering Research Council of Canada RGPIN-2021-03724Sociedad Española de Neumología y Cirugía Torácica (SEPAR) SEPAR 2020Spanish Ministry of Science and Innovation FIS 18/00075Spanish Ministry of Science and Innovation FIS 21/00215
6 · The paper itself

Abstract

The maintenance of mitochondrial integrity is critical for muscle health. Mitochondria, indeed, play vital roles in a wide range of cellular processes, including energy supply, Ca

Indexed as

Mitochondrial DynamicsMitophagyAgingAnimalsHumansMitochondria, MuscleMuscle, SkeletalSarcopeniaagingautophagymitochondrial dynamicsmitophagysarcopeniaskeletal muscle

Identifiers

PMID34360946
PMCPMC8348122
OpenAlexW3192553116

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.