Evidence map›Paper›PMID 34360928›Full record

ArticleInternational journal of molecular sciences2021

Isoconazole and Clemizole Hydrochloride Partially Reverse the Xeroderma Pigmentosum C Phenotype.

Farah Kobaisi, Eric Sulpice, Caroline Barette, Nour Fayyad, Marie-Odile Fauvarque, Bassam Badran, Mohammad Fayyad-Kazan, Hussein Fayyad-Kazan, Xavier Gidrol, Walid Rachidi

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Molecular Effects of Mutations in Human Genetic Diseases.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Farah KobaisiBiomics, IRIG-BGE U1038, INSERM, Univ. Grenoble Alpes, 38000 Grenoble, France.ORCID 0000-0001-9193-1588
Eric SulpiceBiomics, IRIG-BGE U1038, INSERM, Univ. Grenoble Alpes, 38000 Grenoble, France.
Caroline BaretteCEA/IRIG/Gen & Chem, Univ. Grenoble Alpes, 38000 Grenoble, France.
Nour FayyadSYMMES/CIBEST UMR 5819 UGA-CNRS-CEA, IRIG/CEA-Grenoble, Univ. Grenoble Alpes, 38000 Grenoble, France.ORCID 0000-0003-3449-358X
Marie-Odile FauvarqueCEA/IRIG/Gen & Chem, Univ. Grenoble Alpes, 38000 Grenoble, France.ORCID 0000-0001-5020-3701
Bassam BadranLaboratory of Cancer Biology and Molecular Immunology, Faculty of Sciences I, Lebanese University, Hadath, Lebanon.
Mohammad Fayyad-KazanLaboratory of Cancer Biology and Molecular Immunology, Faculty of Sciences I, Lebanese University, Hadath, Lebanon.
Hussein Fayyad-KazanLaboratory of Cancer Biology and Molecular Immunology, Faculty of Sciences I, Lebanese University, Hadath, Lebanon.
Xavier GidrolBiomics, IRIG-BGE U1038, INSERM, Univ. Grenoble Alpes, 38000 Grenoble, France.
Walid RachidiBiomics, IRIG-BGE U1038, INSERM, Univ. Grenoble Alpes, 38000 Grenoble, France.
Inserm · FRLebanese University · LBCommissariat à l'Énergie Atomique et aux Énergies Alternatives · FRCentre National de la Recherche Scientifique · FR

Funding

ANR grant PG2HEAL ANR-18-CE17-0017CBH-EUR-GS ANR-17-EURE-0003Investissements d'avenir ANR-15-IDEX-02Labex GRAL ANR-10-LABX-49-01
6 · The paper itself

Abstract

Xeroderma Pigmentosum protein C (XPC) is involved in recognition and repair of bulky DNA damage such as lesions induced by Ultra Violet (UV) radiation.

Indexed as

BenzimidazolesCell LineCell SurvivalDrug RepositioningHumansMiconazoleSkin DiseasesUltraviolet RaysXeroderma PigmentosumBenzimidazolesclemizoleisoconazoleMiconazolechemical screenDNA damageDNA repairskin cancerUVXPC

Identifiers

PMID34360928
PMCPMC8346964
OpenAlexW3133374083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.