ArticleInternational journal of molecular sciences2021
Peritoneal Fluid from Patients with Ovarian Endometriosis Displays Immunosuppressive Potential and Stimulates Th2 Response.
Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- The deviations of CD4 + T cells during peripheral blood and peritoneal fluid of endometriosis: a systematic review and meta-analysis.Archives of gynecology and obstetrics · 2023Pooled it
- Endometriosis subtypes and risk of type 2 diabetes: the Advancing Research on Cardiovascular Health and Endometriosis Study (ARCHES) retrospective cohort study.Diabetologia · 2026Article
- Targeting the IL-17C-M2 macrophage axis ameliorates fibrosis in endometriosis through MAPK/ERK signaling.Journal of translational medicine · 2026Article
- Endometriosis immune microenvironment timing shifts: from immune escape to immune exhaustion.Cell death discovery · 2026Review
- Endometriosis Is Associated with Increased Serum and Peritoneal Fluid Concentrations of Chromogranin A and Its Derivatives.Journal of clinical medicine · 2026Article
- Immune dysregulation in endometriosis: the T cell perspective.Frontiers in immunology · 2026Review
- Potential biomarkers for early detection of endometriosis: current state of art (what we know so far).Journal of applied genetics · 2025Review
- Exploring the Immune System's Role in Endometriosis: Insights Into Pathogenesis, Pain, and Treatment.Cureus · 2025Review
- The role of the CXC chemokine family in endometriosis research and its therapeutic potential.Journal of molecular histology · 2025Review
- Endometriosis: An Immunologist's Perspective.International journal of molecular sciences · 2025Review
- Review
- Female reproductive disease, endometriosis: From inflammation to infertility.Molecules and cells · 2025Review
- Association Between the C-Reactive Protein-Albumin-Lymphocyte Index and Endometriosis: Insights from the 1999-2006 National Health and Nutrition Examination Survey.International journal of women's health · 2025Article
- Unveiling Potential Blood Markers for Endometriosis Through the Integration and Experimental Validation of Immune Cell Traits Genome and Genome-Wide Associated Data.International journal of women's health · 2025Article
- The correlation between immune cells and endometriosis: a bidirectional two-sample mendelian randomization study.BMC women's health · 2024Article
- The Role of NK and T Cells in Endometriosis.International journal of molecular sciences · 2024Article
- Article
- Mood disorders influencing endometriosis and adenomyosis: Mendelian randomisation study.BJPsych open · 2024Article
- Association of endometriosis with asthma: a study of the NHANES database in 1999-2006.Journal of health, population, and nutrition · 2024Article
- An Estrogen-NK Cells Regulatory Axis in Endometriosis, Related Infertility, and Miscarriage.International journal of molecular sciences · 2024Review
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
Endometriosis is a common gynaecological disorder characterized by the ectopic growth of endometrial tissue outside the uterine cavity. It is associated with chronic pelvic inflammation and autoimmune reactivity manifesting by autoantibody production and abrogated cellular immune responses. Endometriotic peritoneal fluid contains various infiltrating leucocyte populations and a bulk of proinflammatory and immunoregulatory cytokines. However, the nature and significance of the peritoneal milieu in women with endometriosis still remains obscure. Therefore, the aim of the present study was to investigate the immunoregulatory activity of the peritoneal fluid (PF) from women with endometriosis. The peritoneal fluid samples were collected during laparoscopic surgery from 30 women with and without endometriosis. Immunoregulatory cytokines (IL-2, IL-4, IL-6, IL-10, IL-17A, IFN-γ and TNF) and chemokines (CCL2, CCL5, CXCL8 and CXCL9) were evaluated in PF and culture supernatants generated by unstimulated and CD3/CD28/IL-2-stimulated CD4
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.