Evidence map›Paper›PMID 34360822›Full record

ReviewInternational journal of molecular sciences2021

Brillouin Spectroscopy: From Biomedical Research to New Generation Pathology Diagnosis.

Rafael J Jiménez Rioboó, Nuria Gontán, Daniel Sanderson, Manuel Desco, Maria Victoria Gómez-Gaviro

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rafael J Jiménez RioboóInstituto de Ciencia de Materiales de Madrid (ICMM), Consejo Superior de Investigaciones Científicas (CSIC), C/Sor Juana Inés de la Cruz, 3, 28049 Madrid, Spain.
Nuria GontánInstituto de Investigación Sanitaria Gregorio Marañón, 28007 Madrid, Spain.
Daniel SandersonInstituto de Investigación Sanitaria Gregorio Marañón, 28007 Madrid, Spain.
Manuel DescoInstituto de Investigación Sanitaria Gregorio Marañón, 28007 Madrid, Spain.ORCID 0000-0003-0989-3231
Maria Victoria Gómez-GaviroInstituto de Investigación Sanitaria Gregorio Marañón, 28007 Madrid, Spain.ORCID 0000-0002-8683-5150

Funding

Centro de Investigación Biomédica en Red de Salud MentalCentro Nacional de Investigaciones Cardiovasculares SEV-2015-0505European Cooperation in Science and Technology CA16124Instituto de Salud Carlos III PI18/00462
6 · The paper itself

Abstract

Brillouin spectroscopy has recently gained considerable interest within the biomedical field as an innovative tool to study mechanical properties in biology. The Brillouin effect is based on the inelastic scattering of photons caused by their interaction with thermodynamically driven acoustic modes or phonons and it is highly dependent on the material's elasticity. Therefore, Brillouin is a contactless, label-free optic approach to elastic and viscoelastic analysis that has enabled unprecedented analysis of ex vivo and in vivo mechanical behavior of several tissues with a micrometric resolution, paving the way to a promising future in clinical diagnosis. Here, we comprehensively review the different studies of this fast-moving field that have been performed up to date to provide a quick guide of the current literature. In addition, we offer a general view of Brillouin's biomedical potential to encourage its further development to reach its implementation as a feasible, cost-effective pathology diagnostic tool.

Indexed as

Scattering, RadiationAnimalsBone DiseasesHumansNeoplasmsSpectrum Analysisbiological tissuesBrillouin spectroscopydiagnosismechanicsviscoelasticity

Identifiers

PMID34360822
PMCPMC8347166

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.