Using Budding Yeast to Identify Molecules That Block Cancer Cell 'Mitotic Slippage' Only in the Presence of Mitotic Poisons.

Open access · goldAbstract readReview

In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it

0cells of the map it votes in

3citing papers in PubMed

0.2field-weighted citation impact, top 52% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

Small Molecules Identified by an In Silico Docking Screen Targeting Anaphase-Promoting Complex/Cyclosome Subunit 1 (APC1) Potentiate Paclitaxel-Induced Breast Cancer Cell Death.Molecules (Basel, Switzerland) · 2025
Article
Suppressing Anaphase-Promoting Complex/Cyclosome-Cell Division Cycle 20 Activity to Enhance the Effectiveness of Anti-Cancer Drugs That Induce Multipolar Mitotic Spindles.International journal of molecular sciences · 2024
Review
Special Issue: Yeast Cell Signaling Pathways (Volume 1).International journal of molecular sciences · 2023
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Scott C SchuylerDepartment of Biomedical Sciences, College of Medicine, Chang Gung University, Kwei-Shan, Taoyuan 333, Taiwan.ORCID 0000-0002-1844-035X

Hsin-Yu ChenDepartment of Biomedical Sciences, College of Medicine, Chang Gung University, Kwei-Shan, Taoyuan 333, Taiwan.

Chang Gung University · TW

Funding

Chang Gung Memorial Hospital CMRPD1K0121 CMRPD1K0561 CMRPD1J0122 BMRPC59

6 · The paper itself

Abstract

Research on the budding yeast

Indexed as

ApoptosisCell Cycle CheckpointsMitosisNeoplasmsSaccharomyces cerevisiaeAnimalsAntineoplastic AgentsDrug Screening Assays, AntitumorHumansPoisonsAntineoplastic AgentsPoisonsanaphase-promoting complex/cyclosome (APC/C)budding yeastcancercell cyclecell division cycle 20 (Cdc20)mitosismitotic checkpoint complex (MCC)Saccharomyces cerevisiaespindle assembly checkpoint

Identifiers

PMID34360748

DOI10.3390/ijms22157985

PMCPMC8347345

OpenAlexW3186941546

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.