Evidence map›Paper›PMID 34360715›Full record

ArticleInternational journal of molecular sciences2021

Protein Arginine Methyltransferase 1 Is Essential for the Meiosis of Male Germ Cells.

Sahar Waseem, Sudeep Kumar, Kanghoon Lee, Byoung-Ha Yoon, Mirang Kim, Hail Kim, Keesook Lee

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Sahar WaseemSchool of Biological Sciences and Technology, Chonnam National University, Gwangju 61186, Korea.
Sudeep KumarSchool of Biological Sciences and Technology, Chonnam National University, Gwangju 61186, Korea.
Kanghoon LeeBioMedical Research Center, Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon 34141, Korea.
Byoung-Ha YoonPersonalized Genomic Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea.ORCID 0000-0002-5663-5000
Mirang KimPersonalized Genomic Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea.ORCID 0000-0001-7415-0077
Hail KimBioMedical Research Center, Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon 34141, Korea.
Keesook LeeSchool of Biological Sciences and Technology, Chonnam National University, Gwangju 61186, Korea.
Chonnam National University · KRKorea Advanced Institute of Science and Technology · KRKorea Research Institute of Bioscience and Biotechnology · KR

Funding

National Research Foundation of Korea NRF-2017R1A2B4006166National Research Foundation of Korea NRF-2020R1A2C1006705
6 · The paper itself

Abstract

Protein arginine methyltransferase 1 (PRMT1) is a major enzyme responsible for the formation of methylarginine in mammalian cells; however, its function in vivo is not well understood due to its early embryonic lethality in null mice exhibiting spontaneous DNA damage, cell cycle delays, and defects in check point activation. Here, we generated germ cell-specific

Indexed as

MeiosisSpermatogenesisAcid Anhydride HydrolasesAnimalsCell Cycle ProteinsDNA-Binding ProteinsDNA Breaks, Double-StrandedEndodeoxyribonucleasesFemaleGerm CellsMaleMeiotic Recombination Protein SPO11MiceMice, KnockoutMRE11 Homologue ProteinProtein-Arginine N-MethyltransferasesAcid Anhydride HydrolasesCell Cycle ProteinsDNA-Binding ProteinsEndodeoxyribonucleasesMeiotic Recombination Protein SPO11Mre11a protein, mouseMRE11 Homologue ProteinNijmegen breakage syndrome 1 protein, mousePrmt1 protein, mouseProtein-Arginine N-MethyltransferasesRad50 protein, mouseADMADNA double strand break repairmeiosisPRMT1spermatogenesis

Identifiers

PMID34360715
PMCPMC8348183
OpenAlexW3184367116

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.