Evidence map›Paper›PMID 34360647›Full record

ArticleInternational journal of molecular sciences2021

Tumor Promoting Effect of BMP Signaling in Endometrial Cancer.

Tomohiko Fukuda, Risa Fukuda, Kohei Miyazono, Carl-Henrik Heldin

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Review
  3. Discovery of highly potent and ALK2/ALK1 selective kinase inhibitors using DNA-encoded chemistry technology.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. The prognostic value and potential immunotherapeutic efficacy ofJournal of gastrointestinal oncology · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Multifaceted Functions of TWSG1: From Embryogenesis to Cancer Development.International journal of molecular sciences · 2022
    Review
  13. Review
  14. Advances in Gynecological Cancers.International journal of molecular sciences · 2022
    Article
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Tomohiko FukudaScience for Life Laboratory, Department of Medical Biochemistry and Microbiology, Box 582, Uppsala University, SE-751 23 Uppsala, Sweden.ORCID 0000-0003-2711-3067
Risa FukudaScience for Life Laboratory, Department of Medical Biochemistry and Microbiology, Box 582, Uppsala University, SE-751 23 Uppsala, Sweden.
Kohei MiyazonoScience for Life Laboratory, Department of Medical Biochemistry and Microbiology, Box 582, Uppsala University, SE-751 23 Uppsala, Sweden.ORCID 0000-0001-7341-0172
Carl-Henrik HeldinScience for Life Laboratory, Department of Medical Biochemistry and Microbiology, Box 582, Uppsala University, SE-751 23 Uppsala, Sweden.ORCID 0000-0002-9508-896X
Uppsala University · SE

Funding

Cancerfonden 100452European Research Council 787472Vetenskapsrådet 01291
6 · The paper itself

Abstract

The effects of bone morphogenetic proteins (BMPs), members of the transforming growth factor-β (TGF-β) family, in endometrial cancer (EC) have yet to be determined. In this study, we analyzed the TCGA and MSK-IMPACT datasets and investigated the effects of BMP2 and of TWSG1, a BMP antagonist, on Ishikawa EC cells. Frequent

Indexed as

Gene Expression Regulation, NeoplasticApoptosisBiomarkers, TumorBone Morphogenetic Protein 2Bone Morphogenetic Protein 7CarcinogensCell ProliferationEndometrial NeoplasmsFemaleHumansPrognosisSignal TransductionSurvival RateTumor Cells, CulturedBiomarkers, TumorBMP2 protein, humanBMP7 protein, humanBone Morphogenetic Protein 2Bone Morphogenetic Protein 7CarcinogensACVR1BMPcancer stem cellsEMTendometrial cancer

Identifiers

PMID34360647
PMCPMC8346149
OpenAlexW3183973690

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.