Evidence map›Paper›PMID 34360623›Full record

ArticleInternational journal of molecular sciences2021

Bone Status in a Mouse Model of Experimental Autoimmune-Orchitis.

Fabian Hemm, Monika Fijak, Jan Belikan, Marian Kampschulte, Thaqif El Khassawna, Adrian Pilatz, Christian Heiss, Katrin Susanne Lips

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. A Comprehensive Bibliometric Analysis of Orchitis Research from 1980 to 2023.Advances in experimental medicine and biology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Fabian HemmDepartment of Trauma, Hand and Reconstructive Surgery, University Hospital of Giessen, Rudolf-Buchheim-Str. 7, 35392 Giessen, Germany.ORCID 0000-0002-6670-548X
Monika FijakDepartment of Anatomy and Cell Biology, Justus-Liebig-University Giessen, Aulweg 123, 35385 Giessen, Germany.ORCID 0000-0002-7384-3872
Jan BelikanLaboratory of Experimental Radiology, Justus-Liebig-University Giessen, Schubertstrasse 81, 35392 Giessen, Germany.
Marian KampschulteLaboratory of Experimental Radiology, Justus-Liebig-University Giessen, Schubertstrasse 81, 35392 Giessen, Germany.
Thaqif El KhassawnaExperimental Trauma Surgery, Justus-Liebig-University Giessen, Aulweg 128, 35392 Giessen, Germany.ORCID 0000-0002-1187-8578
Adrian PilatzDepartment of Urology, Pediatric Urology and Andrology, University Hospital of Giessen, Rudolf-Buchheim-Straße 7, 35392 Giessen, Germany.
Christian HeissDepartment of Trauma, Hand and Reconstructive Surgery, University Hospital of Giessen, Rudolf-Buchheim-Str. 7, 35392 Giessen, Germany.
Katrin Susanne LipsExperimental Trauma Surgery, Justus-Liebig-University Giessen, Aulweg 128, 35392 Giessen, Germany.ORCID 0000-0003-3320-7545
Justus-Liebig-Universität Gießen · DEUniversitätsklinikum Gießen und Marburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Investigations in male patients with fertility disorders revealed a greater risk of osteoporosis. The rodent model of experimental autoimmune-orchitis (EAO) was established to analyze the underlying mechanisms of male infertility and causes of reduced testosterone concentration. Hence, we investigated the impact of testicular dysfunction in EAO on bone status. Male mice were immunized with testicular homogenate in adjuvant to induce EAO (

Indexed as

AnimalsAutoimmune DiseasesBone and BonesDisease Models, AnimalMaleMiceMice, Inbred C57BLOrchitisOsteoporosisX-Ray Microtomographybiomechanical propertiesexperimental autoimmune-orchitismicro-CTmouse modelosteocalcinosteoporosistestosterone

Identifiers

PMID34360623
PMCPMC8346031
OpenAlexW3184541465

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.