Evidence map›Paper›PMID 34360618›Full record

ArticleInternational journal of molecular sciences2021

Mucus Release and Airway Constriction by TMEM16A May Worsen Pathology in Inflammatory Lung Disease.

Raquel Centeio, Jiraporn Ousingsawat, Inês Cabrita, Rainer Schreiber, Khaoula Talbi, Roberta Benedetto, Tereza Doušová, Eric K Verbeken, Kris De Boeck, Isaac Cohen and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. TMEM16 proteins: CaInternational journal of molecular medicine · 2024
    Review
  7. Review
  8. Article
  9. Specialized proresolving mediator resolvin E1 corrects the altered cystic fibrosis nasal epithelium cilia beating dynamics.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Niclosamide-A promising treatment for COVID-19.British journal of pharmacology · 2022
    Review
  16. Article
  17. Article
  18. Chloride transport modulators as drug candidates.American journal of physiology. Cell physiology · 2021
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Raquel CenteioPhysiological Institute, University of Regensburg, Germany University Street 31, D-93053 Regensburg, Germany.
Jiraporn OusingsawatPhysiological Institute, University of Regensburg, Germany University Street 31, D-93053 Regensburg, Germany.
Inês CabritaPhysiological Institute, University of Regensburg, Germany University Street 31, D-93053 Regensburg, Germany.ORCID 0000-0002-1349-7605
Rainer SchreiberPhysiological Institute, University of Regensburg, Germany University Street 31, D-93053 Regensburg, Germany.ORCID 0000-0002-3974-5363
Khaoula TalbiPhysiological Institute, University of Regensburg, Germany University Street 31, D-93053 Regensburg, Germany.
Roberta BenedettoPhysiological Institute, University of Regensburg, Germany University Street 31, D-93053 Regensburg, Germany.
Tereza DoušováDepartment of Pediatrics, Second Faculty of Medicine, University Hospital Motol, Charles University in Prague, Celetná 13, 116 36 Prague, Czech Republic.ORCID 0000-0002-0184-5035
Eric K VerbekenDepartment of Pathology, University of Leuven, UZ Leuven Campus Gasthuisberg, Herestraat 49, B-3000 Leuven, Belgium.
Kris De BoeckDepartment of Pathology, University of Leuven, UZ Leuven Campus Gasthuisberg, Herestraat 49, B-3000 Leuven, Belgium.
Isaac CohenIaterion, Oakland, CA 94611, USA.
Karl KunzelmannPhysiological Institute, University of Regensburg, Germany University Street 31, D-93053 Regensburg, Germany.ORCID 0000-0001-6222-4593
University of Regensburg · DEUniversitair Ziekenhuis Leuven · BECharles University · CZ

Funding

Cystic Fibrosis Trust SRC013Deutsche Forschungsgemeinschaft DFG KU756/14-1Gilead Sciences Mucus
6 · The paper itself

Abstract

Activation of the Ca

Indexed as

AnimalsAnoctamin-1AsthmaConstriction, PathologicCystic FibrosisHEK293 CellsHumansInflammationMiceMucusRespiratory MucosaAnoctamin-1airwaysasthmabrevenalcystic fibrosisEactETX001TMEM16A

Identifiers

PMID34360618
PMCPMC8346050
OpenAlexW3184067189

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.