Evidence map›Paper›PMID 34360604›Full record

ReviewInternational journal of molecular sciences2021

Tissue-Specific Decellularized Extracellular Matrix Bioinks for Musculoskeletal Tissue Regeneration and Modeling Using 3D Bioprinting Technology.

Wonbin Park, Ge Gao, Dong-Woo Cho

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Wonbin ParkDepartment of Mechanical Engineering, Pohang University of Science and Technology, Pohang 37673, Korea.ORCID 0000-0003-1035-7073
Ge GaoInstitute of Engineering Medicine, Beijing Institute of Technology, Beijing 100081, China.ORCID 0000-0003-3328-2879
Dong-Woo ChoDepartment of Mechanical Engineering, Pohang University of Science and Technology, Pohang 37673, Korea.

Funding

Beijing Institute of Technology Research Fund Program for Young Scholars XSQD-202123003National Research Foundation of Korea 2019R1A3A3005437National Research Foundation of Korea 2020M3H4A1A02084827
6 · The paper itself

Abstract

The musculoskeletal system is a vital body system that protects internal organs, supports locomotion, and maintains homeostatic function. Unfortunately, musculoskeletal disorders are the leading cause of disability worldwide. Although implant surgeries using autografts, allografts, and xenografts have been conducted, several adverse effects, including donor site morbidity and immunoreaction, exist. To overcome these limitations, various biomedical engineering approaches have been proposed based on an understanding of the complexity of human musculoskeletal tissue. In this review, the leading edge of musculoskeletal tissue engineering using 3D bioprinting technology and musculoskeletal tissue-derived decellularized extracellular matrix bioink is described. In particular, studies on in vivo regeneration and in vitro modeling of musculoskeletal tissue have been focused on. Lastly, the current breakthroughs, limitations, and future perspectives are described.

Indexed as

Musculoskeletal DevelopmentRegenerationAnimalsBioprintingExtracellular MatrixHumansMusculoskeletal DiseasesPrinting, Three-DimensionalTissue EngineeringTissue Scaffolds3D bioprintingdecellularized extracellular matrix bioinkmusculoskeletal tissuetissue engineering

Identifiers

PMID34360604
PMCPMC8346156

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.