Evidence map›Paper›PMID 34360598›Full record

ReviewInternational journal of molecular sciences2021

LncRNA

Riccardo Di Fiore, Sherif Suleiman, Rosa Drago-Ferrante, Ana Felix, Sharon A O'Toole, John J O'Leary, Mark P Ward, James Beirne, Angel Yordanov, Mariela Vasileva-Slaveva and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  6. Novel insight into the functions of NInternational journal of oncology · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 7 countries.

Riccardo Di FioreDepartment of Anatomy, Faculty of Medicine and Surgery, University of Malta, MSD 2080 Msida, Malta.ORCID 0000-0003-4905-6948
Sherif SuleimanDepartment of Anatomy, Faculty of Medicine and Surgery, University of Malta, MSD 2080 Msida, Malta.
Rosa Drago-FerranteBioDNA Laboratories, Malta Life Sciences Park, SGN 3000 San Gwann, Malta.
Ana FelixDepartment of Pathology, Instituto Portugues de Oncologia de Lisboa, NOVA Medical School, University NOVA of Lisbon, Campo dos Mártires da Pátria, 130, 1169-056 Lisbon, Portugal.ORCID 0000-0002-2653-2262
Sharon A O'TooleDepartments of Obstetrics and Gynaecology, Trinity St James's Cancer Institute, Trinity College Dublin, D08 HD53 Dublin, Ireland.ORCID 0000-0002-9260-3225
John J O'LearyDepartment of Histopathology, Trinity St James's Cancer Institute, Emer Casey Molecular Pathology Laboratory, Trinity College Dublin and Coombe Women's and Infants University Hospital, D08 RX0X Dublin, Ireland.ORCID 0000-0001-7311-9326
Mark P WardDepartment of Histopathology, Trinity St James's Cancer Institute, Emer Casey Molecular Pathology Laboratory, Trinity College Dublin and Coombe Women's and Infants University Hospital, D08 RX0X Dublin, Ireland.ORCID 0000-0002-9356-7246
James BeirneDepartment of Gynaecological Oncology, Trinity St James's Cancer Institute, St James Hospital, Trinity College Dublin, D08 X4RX Dublin, Ireland.ORCID 0000-0003-3053-3556
Angel YordanovDepartment of Gynecologic Oncology, Medical University Pleven, 5800 Pleven, Bulgaria.ORCID 0000-0002-7719-382X
Mariela Vasileva-SlavevaDepartment of Breast Surgery, Acibadem City Clinic, 1750 Sofia, Bulgaria.ORCID 0000-0002-6180-3742
Yashwanth SubbannayyaCentre of Molecular Inflammation Research (CEMIR), Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, 7491 Trondheim, Norway.ORCID 0000-0002-3885-3514
Francesca PentimalliCell Biology and Biotherapy Unit, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, 80131 Napoli, Italy.ORCID 0000-0003-4740-6801
Antonio GiordanoSbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, PA 19122, USA.
Jean Calleja-AgiusDepartment of Anatomy, Faculty of Medicine and Surgery, University of Malta, MSD 2080 Msida, Malta.ORCID 0000-0001-6369-0297
Trinity College Dublin · IEUniversity of Malta · MTAcibadem City Clinic · BGHeritage Malta · MTIstituto Nazionale Tumori IRCCS "Fondazione G. Pascale" · ITMedical University Pleven · BGNorwegian University of Science and Technology · NOUniversidade Nova de Lisboa · PTUniversity of Siena · IT

Funding

European Cooperation in Science and Technology CA18117
6 · The paper itself

Abstract

Gynecological cancers (GCs) are currently among the major threats to female health. Moreover, there are different histologic subtypes of these cancers, which are defined as 'rare' due to an annual incidence of <6 per 100,000 women. The majority of these tend to be associated with a poor prognosis. Long non-coding RNAs (lncRNAs) play a critical role in the normal development of organisms as well as in tumorigenesis. LncRNAs can be classified into tumor suppressor genes or oncogenes, depending on their function within the cellular context and the signaling pathways in which they are involved. These regulatory RNAs are potential therapeutic targets for cancer due to their tissue and tumor specificity. However, there still needs to be a deeper understanding of the mechanisms by which lncRNAs are involved in the regulation of numerous biological functions in humans, both in normal health and disease. The lncRNA

Indexed as

AnimalsFemaleGenital Neoplasms, FemaleHumansRNA, Long NoncodingMORT long noncoding RNA, humanRNA, Long Noncodingcervical cancerendometrial cancerepigeneticsepigenetic therapylncRNA-based therapylong non-coding RNAMORT (ZNF667-AS1)ovarian cancer

Identifiers

PMID34360598
PMCPMC8346052
OpenAlexW3184929612

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.