Evidence map›Paper›PMID 34360381›Full record

SynthesisInternational journal of environmental research and public health2021

Social Freezing: Pressing Pause on Fertility.

Valentin Nicolae Varlas, Roxana Georgiana Bors, Dragos Albu, Ovidiu Nicolae Penes, Bogdana Adriana Nasui, Claudia Mehedintu, Anca Lucia Pop

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
9.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.

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  20. Social Egg Freezing-A Trend or Modern Reality?Journal of clinical medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Valentin Nicolae VarlasDepartment of Obstetrics and Gynaecology, Filantropia Clinical Hospital, 011171 Bucharest, Romania.ORCID 0000-0002-8342-9819
Roxana Georgiana BorsDepartment of Obstetrics and Gynaecology, Filantropia Clinical Hospital, 011171 Bucharest, Romania.
Dragos AlbuDepartment of Obstetrics and Gynaecology, Filantropia Clinical Hospital, 011171 Bucharest, Romania.
Ovidiu Nicolae PenesDepartment of Intensive Care, University Clinical Hospital, "Carol Davila" University of Medicine and Pharmacy, 37 Dionisie Lupu St., 020021 Bucharest, Romania.
Bogdana Adriana NasuiDepartment of Community Health, "Iuliu Hațieganu" University of Medicine and Pharmacy, 6 Louis Pasteur Street, 400349 Cluj-Napoca, Romania.ORCID 0000-0001-5682-0225
Claudia MehedintuDepartment of Obstetrics and Gynaecology, Nicolae Malaxa Clinical Hospital, 020346 Bucharest, Romania.
Anca Lucia PopDepartment of Clinical Laboratory, Food Safety, "Carol Davila" University of Medicine and Pharmacy, 6 Traian Vuia Street, 020945 Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy · ROClinical Emergency Hospital Bucharest · ROIuliu Hațieganu University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increasing numbers of women are undergoing oocyte or tissue cryopreservation for medical or social reasons to increase their chances of having genetic children. Social egg freezing (SEF) allows women to preserve their fertility in anticipation of age-related fertility decline and ineffective fertility treatments at older ages. The purpose of this study was to summarize recent findings focusing on the challenges of elective egg freezing. We performed a systematic literature review on social egg freezing published during the last ten years. From the systematically screened literature, we identified and analyzed five main topics of interest during the last decade: (a) different fertility preservation techniques, (b) safety of freezing, (c) usage rate of frozen oocytes, (d) ethical considerations, and (e) cost-effectiveness of SEF. Fertility can be preserved for non-medical reasons through oocyte, embryos, or ovarian tissue cryopreservation, with oocyte vitrification being a new and optimal approach. Elective oocyte cryopreservation is better accepted, supports social gender equality, and enhances women's reproductive autonomy. Despite controversies, planned oocyte cryopreservation appears as a chosen strategy against age-related infertility and may allow women to feel that they are more socially, psychologically, and financially stable before motherhood.

Indexed as

Fertility PreservationAgedChildCryopreservationFemaleFertilityHumansMiddle AgedOocytesReproductive Techniques, Assistedage-related infertilitydelayed childbearingelective egg freezingfertility preservationoocyte cryopreservationoocyte vitrificationsocial egg freezing

Identifiers

PMID34360381
PMCPMC8345795
OpenAlexW3190037363

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.