Evidence map›Paper›PMID 34360332›Full record

ArticleInternational journal of environmental research and public health2021

Associations between Physiological Biomarkers and Psychosocial Measures of Pregnancy-Specific Anxiety and Depression with Support Intervention.

Karen L Weis, Tony T Yuan, Katherine C Walker, Thomas F Gibbons, Wenyaw Chan

Registry-linked trialAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04993742 (Effects of Pregnancy-Specific Anxiety on Placental Inflammatory and Oxidative Stress Response and Birth Outcomes), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04993742 naactive not recruitingnot on this map

Effects of Pregnancy-Specific Anxiety on Placental Inflammatory and Oxidative Stress Response and Birth Outcomes (MOMS Placenta)

TypeinterventionalSponsorHenry M. Jackson Foundation for the Advancement of Military MedicineRan2019 to 2026Enrolled150ConditionsPlacental Dysfunction, Prenatal StressArmsMOMS Intervention
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Biomarkers of reproductive psychiatric disorders.The British journal of psychiatry : the journal of mental science · 2025
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Karen L WeisSchool of Nursing and Health Professions, University of the Incarnate Word, 4301 Broadway, CPO #300, San Antonio, TX 78209, USA.
Tony T YuanScience and Technology, 59th Medical Wing, 1632 Nellis St. Bldg. 5406, JBSA-Lackland, TX 78236, USA.
Katherine C WalkerSchool of Nursing and Health Professions, University of the Incarnate Word, 4301 Broadway, CPO #300, San Antonio, TX 78209, USA.
Thomas F GibbonsScience and Technology, 59th Medical Wing, 1632 Nellis St. Bldg. 5406, JBSA-Lackland, TX 78236, USA.
Wenyaw ChanDepartment of Biostatistics and Data Science, School of Public Health, University of Texas-Health Science Center at Houston, 1200 Pressler St., Houston, TX 77030, USA.ORCID 0000-0003-3329-5282

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stress and anxiety significantly impact the hypothalamic-pituitary axis, and in pregnancy, the subsequent maternal-fetal response can lead to poor outcomes. The objective of this study was to assess the association between psychosocial measures of pregnancy-specific anxiety and physiologic inflammatory responses. Specifically, to determine the effectiveness of the Mentors Offering Maternal Support (M-O-M-S

Indexed as

DepressionPregnancy ComplicationsAnxietyAnxiety DisordersBiomarkersFemaleHumansPregnancyStress, PsychologicalBiomarkerscytokinesdepressioninterventionmilitarypregnancyprenatal anxiety

Identifiers

PMID34360332
PMCPMC8345540

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.