Evidence map›Paper›PMID 34359988›Full record

ArticleCells2021

New Data on Organization and Spatial Localization of B-Chromosomes in Cell Nuclei of the Yellow-Necked Mouse

Tatyana Karamysheva, Svetlana Romanenko, Alexey Makunin, Marija Rajičić, Alexey Bogdanov, Vladimir Trifonov, Jelena Blagojević, Mladen Vujošević, Konstantin Orishchenko, Nikolay Rubtsov

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. B Chromosomes' Sequences in Yellow-Necked MiceLife (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Tatyana KaramyshevaInstitute of Cytology and Genetics, The Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.ORCID 0000-0002-5140-4350
Svetlana RomanenkoInstitute of Molecular and Cellular Biology, The Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.ORCID 0000-0002-0951-5209
Alexey MakuninWellcome Sanger Institute, Cambridge CB10 1SA, UK.ORCID 0000-0002-9555-5097
Marija RajičićInstitute for Biological Research "Siniša Stanković", National Institute of Republic of Serbia, 11060 Belgrade, Serbia.ORCID 0000-0002-2470-9888
Alexey BogdanovKoltzov Institute of Developmental Biology, Russian Academy of Sciences, 119991 Moscow, Russia.ORCID 0000-0002-2106-3989
Vladimir TrifonovInstitute of Molecular and Cellular Biology, The Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.ORCID 0000-0003-0454-8359
Jelena BlagojevićInstitute for Biological Research "Siniša Stanković", National Institute of Republic of Serbia, 11060 Belgrade, Serbia.ORCID 0000-0001-7102-5510
Mladen VujoševićInstitute for Biological Research "Siniša Stanković", National Institute of Republic of Serbia, 11060 Belgrade, Serbia.ORCID 0000-0002-5577-4455
Konstantin OrishchenkoInstitute of Cytology and Genetics, The Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.ORCID 0000-0001-9718-9038
Nikolay RubtsovInstitute of Cytology and Genetics, The Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.ORCID 0000-0001-7406-8057
Institute for Biological Research “Siniša Stanković”Novosibirsk State University · RUInstitute of Cytology and Genetics · RUKoltzov Institute of Developmental Biology · RUSiberian Branch of the Russian Academy of Sciences · RUWellcome Sanger Institute · GB

Funding

Government basic research program 0088-2021-0019Russian Foundation for Basic Research 19-015-00084аthe Ministry of Science and Higher Education of the Russian Federation via the Novosibirsk State University 2019-0546 (FSUS-2020-0040)the State Budget of ICG and by the Ministry of Science and Higher Education of the Russian Federation via IC&G SB RAS 0259-2021-0011Wellcome Trust 206194
6 · The paper itself

Abstract

The gene composition, function and evolution of B-chromosomes (Bs) have been actively discussed in recent years. However, the additional genomic elements are still enigmatic. One of Bs mysteries is their spatial organization in the interphase nucleus. It is known that heterochromatic compartments are not randomly localized in a nucleus. The purpose of this work was to study the organization and three-dimensional spatial arrangement of Bs in the interphase nucleus. Using microdissection of Bs and autosome centromeric heterochromatic regions of the yellow-necked mouse (

Indexed as

AnimalsBone Marrow CellsCell NucleusCentromereChromosome PaintingChromosomes, MammalianDNAFibroblastsHumansIn Situ Hybridization, FluorescenceInterphaseMetaphaseMurinaeDNA3D genome organizationB-chromosomes (Bs)chromosome territories (CT)confocal microscopyduplication clustersmicrodissectionrepetitive DNAspeciation

Identifiers

PMID34359988
PMCPMC8305704
OpenAlexW3184487603

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.