Evidence map›Paper›PMID 34359924›Full record

ArticleCells2021

Changes in Chromatin Organization Eradicate Cellular Stress Resilience to UVA/B Light and Induce Premature Aging.

Bela Vasileva, Dessislava Staneva, Natalia Krasteva, George Miloshev, Milena Georgieva

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Natural Deep Eutectic Extracts of Propolis,Oxidative medicine and cellular longevity · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Bela VasilevaLaboratory of Yeast Molecular Genetics, Institute of Molecular Biology, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0002-8718-6412
Dessislava StanevaLaboratory of Yeast Molecular Genetics, Institute of Molecular Biology, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Natalia KrastevaInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0001-7423-7412
George MiloshevLaboratory of Yeast Molecular Genetics, Institute of Molecular Biology, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0003-2979-8899
Milena GeorgievaLaboratory of Yeast Molecular Genetics, Institute of Molecular Biology, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0002-2371-7544
Bulgarian Academy of Sciences · BG

Funding

Bulgarian National Science Fund DN 11/15
6 · The paper itself

Abstract

Complex interactions among DNA and nuclear proteins maintain genome organization and stability. The nuclear proteins, particularly the histones, organize, compact, and preserve the stability of DNA, but also allow its dynamic reorganization whenever the nuclear processes require access to it. Five histone classes exist and they are evolutionarily conserved among eukaryotes. The linker histones are the fifth class and over time, their role in chromatin has been neglected. Linker histones interact with DNA and the other histones and thus sustain genome stability and nuclear organization.

Indexed as

Ultraviolet RaysCell CycleCellular SenescenceChromatinDose-Response Relationship, RadiationGene Expression ProfilingGene Expression Regulation, FungalHistonesMutationSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsStress, PhysiologicalTime FactorsChromatinHistonesSaccharomyces cerevisiae Proteinsactin-related protein 4agingchromatinchronological aginglinker histoneSaccharomyces cerevisiaestress resilienceUVA-B irradiation

Identifiers

PMID34359924
PMCPMC8304177
OpenAlexW3178457947

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.