Evidence map›Paper›PMID 34359878›Full record

ArticleCells2021

Human Tissue Angiotensin Converting Enzyme (ACE) Activity Is Regulated by Genetic Polymorphisms, Posttranslational Modifications, Endogenous Inhibitors and Secretion in the Serum, Lungs and Heart.

Viktor Bánhegyi, Attila Enyedi, Gábor Áron Fülöp, Attila Oláh, Ivetta Mányiné Siket, Csongor Váradi, Klaudia Bottyán, Mária Lódi, Alexandra Csongrádi, Azeem J Umar and 11 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. Article
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  4. Life (Basel, Switzerland) · 2024
    Article
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  6. Article
  7. Article
  8. Article
  9. Article
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  12. Dysregulation of ACE-1 in Normal Aging and the Early Stages of Alzheimer's Disease.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 2 institutions in 1 country.

Viktor BánhegyiDivision of Clinical Physiology, Department of Cardiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Attila EnyediDivision of Thoracic Surgery, Department of Surgery, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Gábor Áron FülöpDivision of Clinical Physiology, Department of Cardiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Attila OláhHeart and Vascular Center, Semmelweis University, 1122 Budapest, Hungary.
Ivetta Mányiné SiketDivision of Clinical Physiology, Department of Cardiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Csongor VáradiDivision of Thoracic Surgery, Department of Surgery, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Klaudia BottyánDivision of Clinical Physiology, Department of Cardiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Mária LódiDivision of Clinical Physiology, Department of Cardiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Alexandra CsongrádiDivision of Clinical Physiology, Department of Cardiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Azeem J UmarDivision of Clinical Physiology, Department of Cardiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Miklós FagyasDivision of Clinical Physiology, Department of Cardiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.ORCID 0000-0003-3262-884X
Dániel CzurigaDivision of Cardiology, Department of Cardiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.ORCID 0000-0002-6972-0781
István ÉdesDivision of Cardiology, Department of Cardiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Miklós PólosHeart and Vascular Center, Semmelweis University, 1122 Budapest, Hungary.
Béla MerkelyHeart and Vascular Center, Semmelweis University, 1122 Budapest, Hungary.
Zoltán CsanádiDivision of Cardiology, Department of Cardiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Zoltán PappDivision of Clinical Physiology, Department of Cardiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Gábor SzabóDepartment of Cardiac Surgery, University of Halle, 06120 Halle (Saale), Germany.
Tamás RadovitsHeart and Vascular Center, Semmelweis University, 1122 Budapest, Hungary.
István TakácsDivision of Thoracic Surgery, Department of Surgery, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Attila TóthDivision of Clinical Physiology, Department of Cardiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.ORCID 0000-0001-6503-3653
University of Debrecen · HUSemmelweis University · HU

Funding

Ministry for Innovation and Technology 2020-4.1.1.-TKP2020Ministry for Innovation and Technology 2.3.2-15-2016-00050Ministry for Innovation and Technology GINOP-2.3.2-15-2016-00043Ministry for Innovation and Technology NVKP_16-1-2016-0017Ministry of Human Capacities ÚNKP-18-3-III-DE-209National Research, Development and Innovation Fund of Hungary FK128809National Research, Development and Innovation Fund of Hungary K132623National Research, Development and Innovation Fund of Hungary K134939Thematic Excellence Programme of the Ministry for Innovation and Technology was also supported by the National Research, Development and Innovation Fund of Hungary ED_18-1-2019-0028Thematic Excellence Programme of the Ministry for Innovation and Technology was also supported by the National Research, Development and Innovation Fund of Hungary TKP2020-IKA-04Thematic Excellence Programme of the Ministry for Innovation and Technology was also supported by the National Research, Development and Innovation Fund of Hungary TKP2020-NKA-04
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedFemaleHumansLungMaleMiddle AgedMyocardiumPeptidyl-Dipeptidase APolymorphism, GeneticProtein Processing, Post-TranslationalACE protein, humanPeptidyl-Dipeptidase AACEangiotensin converting enzymecardiovascular diseasecirculatingheartlungtissue-localized

Identifiers

PMID34359878
PMCPMC8305685
OpenAlexW3182877382

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.