Evidence map›Paper›PMID 34359835›Full record

ArticleCells2021

Integrin-Linked Kinase (ILK) Plays an Important Role in the Laminin-Dependent Development of Dorsal Root Ganglia during Chicken Embryogenesis.

Ewa Mrówczyńska, Antonina Joanna Mazur

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Microenvironment-based immunotherapy in oral cancer: a comprehensive review.Medical oncology (Northwood, London, England) · 2025
    Review
  3. Article
  4. Article
  5. Integrin-linked kinase (ILK): the known vs. the unknown and perspectives.Cellular and molecular life sciences : CMLS · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ewa MrówczyńskaDepartment of Cell Pathology, Faculty of Biotechnology, University of Wroclaw, 50-383 Wroclaw, Poland.ORCID 0000-0002-1204-6108
Antonina Joanna MazurDepartment of Cell Pathology, Faculty of Biotechnology, University of Wroclaw, 50-383 Wroclaw, Poland.ORCID 0000-0002-7561-9030
University of Wrocław · PL

Funding

Narodowe Centrum Nauki 2016/22/E/NZ3/00654
6 · The paper itself

Abstract

Integrin-linked kinase (ILK) is mainly localized in focal adhesions where it interacts and modulates the downstream signaling of integrins affecting cell migration, adhesion, and survival. The interaction of dorsal root ganglia (DRG) cells, being part of the peripheral nervous system (PNS), with the extracellular matrix (ECM) via integrins is crucial for proper PNS development. A few studies have focused on ILK's role in PNS development, but none of these have focused on chicken. Therefore, we decided to investigate ILK's role in the development of

Indexed as

Amino Acid SequenceAnimalsAvian ProteinsCell AdhesionCell MembraneCell MovementCell SurvivalChickensEmbryonic DevelopmentEmbryo, NonmammalianExtracellular MatrixGanglia, SpinalGene Expression Regulation, DevelopmentalLamininNeuronsPeptidesAvian ProteinsLamininlaminin 1PeptidesProtein Serine-Threonine KinasesScaffold Protein ILKaxonal outgrowthchickendorsal root ganglion (DRG)embryogenesisextracellular matrix (ECM)integrin-linked kinase (ILK)lamininperipheral nervous system (PNS)Schwann cell precursors (SCPs)

Identifiers

PMID34359835
PMCPMC8304069
OpenAlexW3173890976

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.