Evidence map›Paper›PMID 34359809›Full record

ReviewCancers2021

MicroRNA and Other Non-Coding RNAs in Epstein-Barr Virus-Associated Cancers.

Kin Israel Notarte, Suranga Senanayake, Imee Macaranas, Pia Marie Albano, Lucia Mundo, Eanna Fennell, Lorenzo Leoncini, Paul Murray

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 3 pooled it
2.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 3 syntheses or guidelines pooled it, 45 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 5 countries.

Kin Israel NotarteFaculty of Medicine & Surgery, University of Santo Tomas, Manila 1008, Philippines.ORCID 0000-0002-6055-0886
Suranga SenanayakeMater Misericordiae University Hospital, D07AX57 Dublin, Ireland.ORCID 0000-0002-5668-569X
Imee MacaranasFaculty of Medicine & Surgery, University of Santo Tomas, Manila 1008, Philippines.ORCID 0000-0001-6639-0732
Pia Marie AlbanoResearch Center for the Natural and Applied Sciences, Molecular Diagnostics Research Group, University of Santo Tomas, Manila 1015, Philippines.
Lucia MundoDepartment of Medical Biotechnologies, Section of Pathology, University of Siena, 53100 Siena, Italy.
Eanna FennellHealth Research Institute, University of Limerick, V94 T9PX Limerick, Ireland.ORCID 0000-0002-1280-3439
Lorenzo LeonciniDepartment of Medical Biotechnologies, Section of Pathology, University of Siena, 53100 Siena, Italy.
Paul MurrayHealth Research Institute, University of Limerick, V94 T9PX Limerick, Ireland.
University of Santo Tomas · PHUniversity of Limerick · IEUniversity of Siena · ITMater Misericordiae University Hospital · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

EBV is a direct causative agent in around 1.5% of all cancers. The oncogenic properties of EBV are related to its ability to activate processes needed for cellular proliferation, survival, migration, and immune evasion. The EBV latency program is required for the immortalization of infected B cells and involves the expression of non-coding RNAs (ncRNAs), including viral microRNAs. These ncRNAs have different functions that contribute to virus persistence in the asymptomatic host and to the development of EBV-associated cancers. In this review, we discuss the function and potential clinical utility of EBV microRNAs and other ncRNAs in EBV-associated malignancies. This review is not intended to be comprehensive, but rather to provide examples of the importance of ncRNAs.

Indexed as

Burkitt lymphomacarcinogenesisclassical Hodgkin’s lymphomadiffuse large B-cell lymphomaEBVgastric carcinomaimmune evasionmicroRNAomemiRNAnasopharyngeal carcinoma

Identifiers

PMID34359809
PMCPMC8345394
OpenAlexW3192516798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.