Evidence map›Paper›PMID 34359726›Full record

ArticleCancers2021

Randomized Trial Assessing the Impact of Routine Assessment of Health-Related Quality of Life in Patients with Head and Neck Cancer.

Oumar Billa, Franck Bonnetain, Jérôme Chamois, Angeline Ligey, Valérie Ganansia, Georges Noel, Sophie Renard, Sophie Maillard, Magali Quivrin, Noémie Vulquin and 3 more

Abstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Predictive value of health-related quality of life on radiotherapy-related toxicities in patients with head and neck cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Oumar BillaGeorges-François Leclerc Cancer Centre-UNICANCER, Epidemiology and Quality of Life Unit, 21000 Dijon, France.
Franck BonnetainMethodology and Quality of Life in Oncology Unit, Inserm UMR 1098, University Hospital of Besancon, 25000 Besancon, France.
Jérôme ChamoisGeorges-François Leclerc Cancer Centre-UNICANCER, Radiotherapy Department, 1 Rue Professeur Marion, 21000 Dijon, France.
Angeline LigeyCentre Hospitalier Fleriat, 01012 Bourg-en-Bresse, France.
Valérie GanansiaPaul Strauss Cancer Centre-Unicancer, 67000 Strasbourg, France.
Georges NoelPaul Strauss Cancer Centre-Unicancer, 67000 Strasbourg, France.
Sophie RenardInstitut de cancérologie de Lorraine, 54519 Vandœuvre-lès-Nancy, France.
Sophie MaillardCentre Bourgogne, 59000 Lille, France.
Magali QuivrinGeorges-François Leclerc Cancer Centre-UNICANCER, Radiotherapy Department, 1 Rue Professeur Marion, 21000 Dijon, France.
Noémie VulquinGeorges-François Leclerc Cancer Centre-UNICANCER, Radiotherapy Department, 1 Rue Professeur Marion, 21000 Dijon, France.
Pierre TruntzerPaul Strauss Cancer Centre-Unicancer, 67000 Strasbourg, France.
Tienhan Sandrine Dabakuyo-YonliGeorges-François Leclerc Cancer Centre-UNICANCER, Epidemiology and Quality of Life Unit, 21000 Dijon, France.ORCID 0000-0002-8191-1222
Philippe MaingonGeorges-François Leclerc Cancer Centre-UNICANCER, Radiotherapy Department, 1 Rue Professeur Marion, 21000 Dijon, France.ORCID 0000-0001-5364-9979

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The impact of routine assessment of health-related quality of life (HRQoL) on satisfaction with care and the HRQoL of patients with head and neck cancer (HNC) treated with radiotherapy was assessed. Patients with HNC were randomly assigned to two arms, with stratification on sex, cancer localization, and stage of the disease. In the intervention arm, the patients completed the EORTC QLQ-C30 and EORTC QLQ-H&N35 questionnaires first before randomization, then before each medical appointment during radiotherapy (7 weeks), and then every 3 months until 1 year and at 2 years thereafter. In the control arm, the EORTC QLQ-C30 and EORTC QLQ-H&N35 questionnaires were completed before randomization and at 1 year and 2 years thereafter. The primary endpoint was mean change in HRQoL at score at 2 years from baseline assessed by EQ VAS from the EuroQol questionnaire. The secondary endpoint was mean change in satisfaction with care at 2 years from baseline assessed by QLQ-SAT32. Two hundred patients with head and neck cancers were involved in this study (mean age, 58.83 years (range, 36.56-87.89)), of whom 100 were assigned to the intervention arm and 100 to the control arm. Patients in the intervention arm were reported to have a statistically significant increase in EQ VAS at 2 years (

Indexed as

head and neck cancerquality of liferoutine assessment

Identifiers

PMID34359726
PMCPMC8345055

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.