Evidence map›Paper›PMID 34359695›Full record

ArticleCancers2021

ALBI Score Is a Strong Predictor of Toxicity Following SIRT for Hepatocellular Carcinoma.

Céline Lescure, Florian Estrade, Maud Pedrono, Boris Campillo-Gimenez, Samuel Le Sourd, Marc Pracht, Xavier Palard, Héloïse Bourien, Léa Muzellec, Thomas Uguen and 3 more

Abstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Impact of Child Pugh B Stage for the Treatment of Advanced HCC.Journal of hepatocellular carcinoma · 2026
    Review
  7. Review
  8. Article
  9. PET/CT-Based Absorbed Dose Maps inJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Céline LescureCentre Eugène Marquis, Medical Oncology, 35043 Rennes, France.
Florian EstradeCentre Eugène Marquis, Medical Oncology, 35043 Rennes, France.ORCID 0000-0001-7559-194X
Maud PedronoCentre Eugène Marquis, Medical Oncology, 35043 Rennes, France.
Boris Campillo-GimenezCentre Eugène Marquis, Clinical Research, 35043 Rennes, France.
Samuel Le SourdCentre Eugène Marquis, Medical Oncology, 35043 Rennes, France.
Marc PrachtCentre Eugène Marquis, Medical Oncology, 35043 Rennes, France.ORCID 0000-0001-8110-0780
Xavier PalardCentre Eugène Marquis, Nuclear Medicine, 35043 Rennes, France.
Héloïse BourienCentre Eugène Marquis, Medical Oncology, 35043 Rennes, France.
Léa MuzellecCentre Eugène Marquis, Medical Oncology, 35043 Rennes, France.
Thomas UguenCHU Pontchaillou, Hepatology, 35043 Rennes, France.
Yan RollandCentre Eugène Marquis, Interventional Radiology, 35043 Rennes, France.
Etienne GarinCentre Eugène Marquis, Nuclear Medicine, 35043 Rennes, France.
Julien EdelineCentre Eugène Marquis, Medical Oncology, 35043 Rennes, France.ORCID 0000-0002-8289-7741

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSelective internal radiation therapy (SIRT) is an innovative treatment of hepatocellular carcinoma (HCC). The albumin-bilirubin (ALBI) score was designed to better evaluate liver functions in HCC.

methodsWe studied, retrospectively, data from patients treated with SIRT for HCC. The primary endpoint was the occurrence of radioembolization-induced liver disease (REILD). The secondary endpoint was overall survival (OS).

results222 patients were studied. The ALBI grade 1 patients had significantly less REILD (3.4%) after the first SIRT than ALBI grade 2 or 3 patients (16.8%,

conclusionsThe baseline ALBI grade is a strong predictor of REILD. The baseline ALBI score and variations of ALBI are prognostic after SIRT.

Indexed as

liver functionradioembolizationtoxicityYttrium-90

Identifiers

PMID34359695
PMCPMC8345032

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.