Evidence map›Paper›PMID 34359643›Full record

ArticleCancers2021

Adjuvant Radiotherapy Significantly Increases Neck Control and Survival in Early Oral Cancer Patients with Solitary Nodal Involvement: A National Cancer Registry Database Analysis.

Chia-Jen Tsai, Yu-Hsuan Kuo, Hung-Chang Wu, Chung-Han Ho, Yi-Chen Chen, Ching-Chieh Yang

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

  1. Postoperative Lymph Is a Proximal Source of ctDNA for Detection of Recurrence in HPV-Independent Head and Neck Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chia-Jen TsaiDepartment of Radiation Oncology, Chi Mei Medical Center, Tainan 71069, Taiwan.
Yu-Hsuan KuoDivision of Hematology and Oncology, Department of Internal Medicine, Chi Mei Medical Center, Tainan 71069, Taiwan.
Hung-Chang WuDivision of Hematology and Oncology, Department of Internal Medicine, Chi Mei Medical Center, Tainan 71069, Taiwan.
Chung-Han HoDepartment of Medical Research, Chi Mei Medical Center, Tainan 71069, Taiwan.
Yi-Chen ChenDepartment of Medical Research, Chi Mei Medical Center, Tainan 71069, Taiwan.
Ching-Chieh YangDepartment of Radiation Oncology, Chi Mei Medical Center, Tainan 71069, Taiwan.ORCID 0000-0003-3823-4673
Chi Mei Medical Center · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We assessed the role of adjuvant radiotherapy on neck control and survival in patients with early oral cancer with solitary nodal involvement. We identified pT1-2N1 oral cancer patients with or without adjuvant radiotherapy from the 2007-2015 Taiwan Cancer Registry database. The effect of adjuvant radiotherapy on 5-year neck control, overall survival (OS) and disease-free survival (DFS) were calculated using the Kaplan-Meier method, log-rank tests, and Cox regression analysis. Of 701 patients identified, 505 (72.0%) received adjuvant radiotherapy and 196 (28.0%) had surgery alone. Patients receiving adjuvant radiotherapy were more likely to be aged <65 years, pT2 stage, poorly graded and without comorbid conditions (all,

Indexed as

adjuvant radiotherapyneck controloral cancerpN1survival

Identifiers

PMID34359643
PMCPMC8345217
OpenAlexW3184814418

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.