ReviewFoods (Basel, Switzerland)2021
Potential Effects of Phenolic Compounds That Can Be Found in Olive Oil on Wound Healing.
Review in Foods (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06070311 (Effect of Thymoquinone and Olive Oil on Wound Healing After Endoscopic Sinus Surgery in Patients With Nasal Polyposis), which is not on this map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Thymoquinone and Olive Oil on Wound Healing After Endoscopic Sinus Surgery in Patients With Nasal Polyposis
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.
- Efficacy and Safety of Topical Application of Olive Oil for Preventing Pressure Ulcers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.International journal of environmental research and public health · 2022Pooled it
- Comparative Investigation of Red Wine Concentrates as Multifunctional Skin-Protective Agents.Pharmaceutics · 2026Article
- Comparative Phytochemical Profiling and Wound Healing Potential ofFood science & nutrition · 2026Article
- Histological Evaluation ofBiomedicines · 2026Article
- A novel collagen hydrogel loaded with primary brown sugar for accelerating burn wound healing by a synergistic mechanism.Regenerative biomaterials · 2026Article
- Phytochemical Analysis, In Vitro and In Vivo Evaluation of Ficus altissima Extract-Based Ointment and Hydrogel on Wound Healing.BioMed research international · 2026Article
- The Influence of Phyto-Active Incorporated Topical Formulations on Cell Migration in Scratch Assays andCurrent drug delivery · 2026Article
- Bioactive Hydrogel Dressings Incorporating Decellularized Ovine Liver Extracellular Matrix (ECM) for Effective Wound Regeneration.BioMed research international · 2026Article
- Natural Compound-Loaded PLGA Nanocarriers for Infected Wound Management: A Review.International journal of nanomedicine · 2026Review
- Phytotherapeutic evaluation of rosehip seed and olive oils on wound healing: evidence from L929 cell culture and in vivo VEGF/TGF-β analysis.3 Biotech · 2025Article
- Maternal Extra Virgin Olive Oil Supplementation Enhances Offspring Immune Function: A Preclinical Study.International journal of molecular sciences · 2025Article
- Impact of Extra-Virgin Olive Oil Storage Conditions on Phenolic Content and Wound-Healing Properties.Foods (Basel, Switzerland) · 2025Article
- Vanillin Enhances Photobiomodulation Wound Healing by Modulating Glyco-Oxidative Stress and Glucose Dysmetabolism in Diabetic Wounded Fibroblast Cells.Journal of cellular and molecular medicine · 2025Article
- Characterization of Chitosan Persian Gum Hydrogel Containing Jaft and Yarrow Extracts for Enhanced Wound Healing.BioMed research international · 2025Article
- Healing effects of topically applied Ocimum basilicum L. on excisional wounds in mice.Acta cirurgica brasileira · 2025Article
- Assessment ofBiomolecules · 2024Article
- Article
- The Anti-Inflammatory Potential of an Ethanolic Extract fromInternational journal of molecular sciences · 2024Article
- Article
- Sodium alginate/carboxymethylcellulose gel formulations containingTherapeutic delivery · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The treatment of tissue damage produced by physical, chemical, or mechanical agents involves considerable direct and indirect costs to health care systems. Wound healing involves a series of molecular and cellular events aimed at repairing the defect in tissue integrity. These events can be favored by various natural agents, including the polyphenols in extra virgin olive oil (EVOO). The objective of this study was to review data on the potential effects of different phenolic compounds that can also be found in EVOO on wound healing and closure. Results of in vitro and animal studies demonstrate that polyphenols from different plant species, also present in EVOO, participate in different aspects of wound healing, accelerating this process through their anti-inflammatory, antioxidant, and antimicrobial properties and their stimulation of angiogenic activities required for granulation tissue formation and wound re-epithelialization. These results indicate the potential usefulness of EVOO phenolic compounds for wound treatment, either alone or in combination with other therapies. Human studies are warranted to verify this proposition.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.