Evidence map›Paper›PMID 34359368›Full record

ReviewDiagnostics (Basel, Switzerland)2021

Optical-Based Biosensors and Their Portable Healthcare Devices for Detecting and Monitoring Biomarkers in Body Fluids.

Anh Tran Tam Pham, Angus Wallace, Xinyi Zhang, Damian Tohl, Hao Fu, Clarence Chuah, Karen J Reynolds, Carolyn Ramsey, Youhong Tang

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
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  6. Article
  7. Review
  8. Review
  9. Smartphone-Enabled Colorimetry.Sensors (Basel, Switzerland) · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Anh Tran Tam PhamAustralia-China Science and Research Fund Joint Research Centre for Personal Health Technologies, Flinders University, Tonsley, SA 5042, Australia.
Angus WallaceAustralia-China Science and Research Fund Joint Research Centre for Personal Health Technologies, Flinders University, Tonsley, SA 5042, Australia.
Xinyi ZhangAustralia-China Science and Research Fund Joint Research Centre for Personal Health Technologies, Flinders University, Tonsley, SA 5042, Australia.
Damian TohlAustralia-China Science and Research Fund Joint Research Centre for Personal Health Technologies, Flinders University, Tonsley, SA 5042, Australia.
Hao FuAustralia-China Science and Research Fund Joint Research Centre for Personal Health Technologies, Flinders University, Tonsley, SA 5042, Australia.
Clarence ChuahMedical Device Research Institute, Flinders University, Tonsley, SA 5042, Australia.
Karen J ReynoldsAustralia-China Science and Research Fund Joint Research Centre for Personal Health Technologies, Flinders University, Tonsley, SA 5042, Australia.ORCID 0000-0002-8273-1610
Carolyn RamseyAustralia-China Science and Research Fund Joint Research Centre for Personal Health Technologies, Flinders University, Tonsley, SA 5042, Australia.
Youhong TangAustralia-China Science and Research Fund Joint Research Centre for Personal Health Technologies, Flinders University, Tonsley, SA 5042, Australia.ORCID 0000-0003-2718-544X
Flinders University · AU

Funding

Australia-China Science and Research Fund the Joint Research Centre for Personal Health Technologies
6 · The paper itself

Abstract

The detection and monitoring of biomarkers in body fluids has been used to improve human healthcare activities for decades. In recent years, researchers have focused their attention on applying the point-of-care (POC) strategies into biomarker detection. The evolution of mobile technologies has allowed researchers to develop numerous portable medical devices that aim to deliver comparable results to clinical measurements. Among these, optical-based detection methods have been considered as one of the common and efficient ways to detect and monitor the presence of biomarkers in bodily fluids, and emerging aggregation-induced emission luminogens (AIEgens) with their distinct features are merging with portable medical devices. In this review, the detection methodologies that use optical measurements in the POC systems for the detection and monitoring of biomarkers in bodily fluids are compared, including colorimetry, fluorescence and chemiluminescence measurements. The current portable technologies, with or without the use of smartphones in device development, that are combined with optical biosensors for the detection and monitoring of biomarkers in body fluids, are also investigated. The review also discusses novel AIEgens used in the portable systems for the detection and monitoring of biomarkers in body fluid. Finally, the potential of future developments and the use of optical detection-based portable devices in healthcare activities are explored.

Indexed as

biomarkersbiosensorsbody fluidsdevicesdiagnosticsoptical detectionspoint-of-care

Identifiers

PMID34359368
PMCPMC8307945
OpenAlexW3185260998

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.