Evidence map›Paper›PMID 34359302›Full record

GuidelineDiagnostics (Basel, Switzerland)2021

Guidelines for Point-of-Care Fluorescence Imaging for Detection of Wound Bacterial Burden Based on Delphi Consensus.

Alisha R Oropallo, Charles Andersen, Raymond Abdo, Jenny Hurlow, Martha Kelso, Mark Melin, Thomas E Serena

Open access · goldAbstract readGuideline
In one paragraph

Guideline in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 29 citations in OpenAlex.

  1. Trial
  2. Review
  3. A Scoping Review of Fluorescence Imaging: A Promising New Technology for Bacterial Detection in Burn Wounds.Journal of burn care & research : official publication of the American Burn Association · 2026
    Article
  4. Review
  5. The Immunostimulatory Effect of MIL-101(Al)-NHInternational journal of molecular sciences · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Observational
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Alisha R OropalloComprehensive Wound Healing Center and Hyperbarics, Department of Vascular Surgery, Zucker School of Medicine Hofstra/Northwell, Hempstead, NY 11549, USA.
Charles AndersenWound Care Clinic, Madigan Army Medical Center Joint Base Lewis-McChord, Renton, WA 98431, USA.
Raymond AbdoSt. Louis Foot & Ankle, LLC., St. Louis, MO 63109, USA.
Jenny HurlowConsultant Wound Care Specialized Nurse Practitioner, Memphis, TN 37501, USA.
Martha KelsoWound Care Plus, LLC., Blue Springs, MO 64015, USA.
Mark MelinM Health Fairview Wound Healing Institute, South Campus, Edina, MN 55435, USA.ORCID 0000-0002-1368-0426
Thomas E SerenaSerenaGroup Research Foundation, 125 Cambridge Park Dr., Cambridge, MA 02140, USA.ORCID 0000-0003-1032-3578
Healing Institute · USMadigan Army Medical Center · USSerenaGroup Research Institute · USWound Healing Society · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Excessive levels of bacteria impede wound healing and can lead to infectious complications. Unfortunately, clinical signs and symptoms of elevated bacterial burden are often unreliable. As a result, point--of--care fluorescence imaging, used to detect critical bacterial burden in wounds, is becoming widely recognized and adopted by clinicians across the globe as an accepted and added component of wound assessment protocol. A Delphi method was employed to establish consensus guidelines describing fluorescence imaging use. A multidisciplinary panel of 32 wound experts (56% MD, 22% podiatrist, 12.5% nurses/nurse practitioners) representing multiple sites of service (e.g., hospital outpatient, inpatient, private office, long-term care) completed two rounds of online questionnaires. The Delphi included key topics, including competencies required to perform imaging, clinical indications for imaging (e.g., signs/symptoms present, procedures warranting imaging), frequency of imaging, and a clinical workflow algorithm. Describing their clinical experiences of imaging impact, >80% reported changes in treatment plans, 96% reported that imaging-informed treatment plans led to improved wound healing, 78% reported reduced rates of amputations, and 83% reported reduced rates of microbiological sampling. The guidelines provided here will help to standardize use of fluorescence imaging among wound care providers and enhance the quality of patient care.

Indexed as

bacteriaconsensusDelphi methodfluorescence imagingguidelinesMolecuLightwound care

Identifiers

PMID34359302
PMCPMC8303157
OpenAlexW3177731152

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.