Evidence map›Paper›PMID 34359278›Full record

ReviewAnimals : an open access journal from MDPI2021

Isothermal Nucleic Acid Amplification Technologies for the Detection of Equine Viral Pathogens.

Alexandra Knox, Travis Beddoe

Open access · goldAbstract readReview
In one paragraph

Review in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Exploring the diagnostic landscape ofFrontiers in microbiology · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Virus Infection in Equine.Animals : an open access journal from MDPI · 2022
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alexandra KnoxDepartment of Animal, Plant and Soil Sciences and Centre for AgriBioscience La Trobe University, Bundoora, VIC 2082, Australia.
Travis BeddoeDepartment of Animal, Plant and Soil Sciences and Centre for AgriBioscience La Trobe University, Bundoora, VIC 2082, Australia.ORCID 0000-0003-4550-2277
La Trobe University · AU

Funding

Cooperative Research Centres Project n/aDefence Science Institute n/a
6 · The paper itself

Abstract

The global equine industry provides significant economic contributions worldwide, producing approximately USD $300 billion annually. However, with the continuous national and international movement and importation of horses, there is an ongoing threat of a viral outbreak causing large epidemics and subsequent significant economic losses. Additionally, horses serve as a host for several zoonotic diseases that could cause significant human health problems. The ability to rapidly diagnose equine viral diseases early could lead to better management, treatment, and biosecurity strategies. Current serological and molecular methods cannot be field-deployable and are not suitable for resource-poor laboratories due to the requirement of expensive equipment and trained personnel. Recently, isothermal nucleic acid amplification technologies, such as loop-mediated isothermal amplification (LAMP) and insulated isothermal polymerase chain reaction (iiPCR), have been developed to be utilized in-field, and provide rapid results within an hour. We will review current isothermal diagnostic techniques available to diagnose equine viruses of biosecurity and zoonotic concern and provide insight into their potential for in-field deployment.

Indexed as

equinefield-deployableinsulated isothermal polymerase chain reactionloop-mediated isothermal amplificationpoint-of-care testingviruses

Identifiers

PMID34359278
PMCPMC8300645
OpenAlexW3185451321

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.