Evidence map›Paper›PMID 34359262›Full record

ReviewAnimals : an open access journal from MDPI2021

Fighting Like Cats and Dogs: Challenges in Domestic Carnivore Oocyte Development and Promises of Innovative Culture Systems.

Martina Colombo, Isa Mohammed Alkali, Sylwia Prochowska, Gaia Cecilia Luvoni

Open access · goldAbstract readReview
In one paragraph

Review in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Morphological and Functional Evaluation of Kodkod (Animals : an open access journal from MDPI · 2025
    Article
  3. Seasonal and age effects onFrontiers in veterinary science · 2025
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Martina ColomboDipartimento di Scienze Veterinarie per la Salute, la Produzione Animale e la Sicurezza Alimentare "Carlo Cantoni", Università degli Studi di Milano, 26900 Lodi, Italy.ORCID 0000-0003-1436-1985
Isa Mohammed AlkaliDipartimento di Scienze Veterinarie per la Salute, la Produzione Animale e la Sicurezza Alimentare "Carlo Cantoni", Università degli Studi di Milano, 26900 Lodi, Italy.
Sylwia ProchowskaDepartment of Reproduction and Clinic of Farm Animals, Wrocław University of Environmental and Life Sciences, Grunwaldzki Square 49, 50-366 Wrocław, Poland.ORCID 0000-0002-5708-8141
Gaia Cecilia LuvoniDipartimento di Scienze Veterinarie per la Salute, la Produzione Animale e la Sicurezza Alimentare "Carlo Cantoni", Università degli Studi di Milano, 26900 Lodi, Italy.ORCID 0000-0002-9598-9098
University of Milan · ITWrocław University of Environmental and Life Sciences · PL

Funding

Polish National Agency for Academic Exchange PPI/APM/2019/1/00044/U/00001Regione Lombardia PSR INNOVA n.201801061529Università degli Studi di Milano Piano di Sostegno alla Ricerca 2019 (Linea 2 Azione A)Università degli Studi di Milano PSR 2019_DIP_027_ALUCI_01
6 · The paper itself

Abstract

In vitro embryo production in cats and dogs still presents some challenges, and it needs to be optimized to transfer efficient protocols to related wild, endangered species. While the chemical composition of culture media has been the focus of several studies, the importance of culture substrates for oocyte and embryo culture has often been neglected. Traditional in vitro systems, i.e., two-dimensional cultures, do not resemble the physiological environments where cells develop, and they may cause morphological and functional alterations to oocytes and embryos. More modern three-dimensional and microfluidic culture system better mimic the structure and the stimuli found in in vivo conditions, and they could better support the development of oocytes and embryos in vitro, as well as the maintenance of more physiological behaviors. This review describes the different culture systems tested for domestic carnivore reproductive cells along the years, and it summarizes their effects on cultured cells with the purpose of analyzing innovative options to improve in vitro embryo production outcomes.

Indexed as

3Dcanineco-culturefelineIVCIVFIVMmicrofluidic

Identifiers

PMID34359262
PMCPMC8300176
OpenAlexW3185176035

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.