ArticleAnimals : an open access journal from MDPI2021
Absence of SARS-CoV-2 Antibodies in Natural Environment Exposure in Sheep in Close Contact with Humans.
Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 15 citations in OpenAlex.
- Seroprevalence of SARS-CoV-2 in Livestock in Sarawak, East Malaysia.Transboundary and emerging diseases · 2026Article
- Presence of anti-SARS-CoV-2 antibodies in European bison (Bison bonasus) in Poland, 2019-2023.BMC veterinary research · 2025Article
- Some Zoonotic Antigens May Help Combat Unknown Pathogens: Forming the Puzzle from the Evidences in the COVID Era.Infectious disorders drug targets · 2025Article
- Investigating SARS-CoV-2 Neutralising Antibody Response in Sheep.Microorganisms · 2024Article
- Cattle, sheep, and goat humoral immune responses against SARS-CoV-2.Veterinary and animal science · 2024Article
- Improving the ONE HEALTH approach: a lesson from SARS-CoV-2 pandemic.Journal of preventive medicine and hygiene · 2024Review
- Molecular surveillance of potential SARS-CoV-2 reservoir hosts in wildlife rehabilitation centers.The veterinary quarterly · 2023Article
- First serological evidence of SARS-CoV-2 natural infection in small ruminants : Brief report.Veterinary research communications · 2023Article
- SARS-CoV-2 in animals: susceptibility of animal species, risk for animal and public health, monitoring, prevention and control.EFSA journal. European Food Safety Authority · 2023Article
- Susceptibility of sheep to experimental co-infection with the ancestral lineage of SARS-CoV-2 and its alpha variant.Emerging microbes & infections · 2022Article
- No Evidence of SARS-CoV-2 Infection in Wild Mink (Animals : an open access journal from MDPI · 2022Article
- Susceptibility of sheep to experimental co-infection with the ancestral lineage of SARS-CoV-2 and its alpha variant.bioRxiv : the preprint server for biology · 2021Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the zoonotic causative agent of coronavirus disease 2019 (COVID-19) that has caused a pandemic situation with millions of infected humans worldwide. Among domestic animals, there have been limited studies regarding the transmissibility and exposure to the infection in natural conditions. Some animals are exposed and/or susceptible to SARS-CoV-2 infection, such as cats, ferrets and dogs. By contrast, there is no information about the susceptibility of ruminants to SARS-CoV-2. This study tested the antibody response in 90 ovine pre-pandemic serum samples and 336 sheep serum samples from the pandemic period (June 2020 to March 2021). In both cases, the animals were in close contact with a veterinary student community composed of more than 700 members. None of the serum samples analyzed was seroreactive based on an enzyme-linked immunosorbent assay (ELISA) using the receptor-binding domain (RBD) of the spike antigen. In this sense, no statistical difference was observed compared to the pre-pandemic sheep. Our results suggest that it seems unlikely that sheep could play a relevant role in the epidemiology of SARS-CoV-2 infection. This is the first study to report the absence of evidence of sheep exposure to SARS-CoV-2 in natural conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.