Evidence map›Paper›PMID 34358719›Full record

ArticleClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2022

Cytosponge-TFF3 Testing can Detect Precancerous Mucosal Changes of the Stomach.

Andreas V Hadjinicolaou, Alexander A Azizi, Maria O'Donovan, Irene Debiram, Rebecca C Fitzgerald, Massimiliano Di Pietro

Registry-linked trialAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05657080 (An Investigation on Cytosponge and Molecular Biomarkers to Identify Patients With Gastric Intestinal Metaplasia), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05657080 unknown statusnot on this mapstarted 2023, after this paper: background citation

An Investigation on Cytosponge and Molecular Biomarkers to Identify Patients With Gastric Intestinal Metaplasia (GIM)

TypeobservationalSponsorUniversity of CambridgeRan2023 to 2024Enrolled226ConditionsGastric Cancer, Gastric Intestinal Metaplasia, Gastric AtrophyArmsCytosponge-TFF3
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andreas V HadjinicolaouMRC Cancer Unit, University of Cambridge, Cambridge, United Kingdom; Department of Digestive Diseases, Addenbrooke's Hospital, Cambridge, United Kingdom.
Alexander A AziziDepartment of Clinical Pharmacology and Therapeutics, Addenbrooke's Hospital, Cambridge, United Kingdom.
Maria O'DonovanDepartment of Histopathology, Addenbrooke's Hospital, Cambridge, United Kingdom.
Irene DebiramMRC Cancer Unit, University of Cambridge, Cambridge, United Kingdom.
Rebecca C FitzgeraldMRC Cancer Unit, University of Cambridge, Cambridge, United Kingdom.
Massimiliano Di PietroMRC Cancer Unit, University of Cambridge, Cambridge, United Kingdom; Department of Digestive Diseases, Addenbrooke's Hospital, Cambridge, United Kingdom. Electronic address: md460@cam.ac.uk.

Funding

Cancer Research UK 21047Medical Research Council MC_UU_12022/2Medical Research Council MR/W014122/1
6 · The paper itself

Abstract

Gastric intestinal metaplasia (GIM) and gastric atrophy (GA) are associated with increased risk of gastric cancer and are indications for endoscopic surveillance when affecting the proximal stomach.

Indexed as

Gastric MucosaPrecancerous ConditionsStomach NeoplasmsEndoscopyHumansMetaplasiaTrefoil Factor-3TFF3 protein, humanTrefoil Factor-3

Identifiers

PMID34358719
PMCPMC9130737

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.