Evidence map›Paper›PMID 34358413›Full record

ReviewThe FEBS journal2022

Arginine methylation in the epithelial-to-mesenchymal transition.

Jian Qin, Jian Xu

Open access · bronzeAbstract readReview
In one paragraph

Review in The FEBS journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Characterization of Alternative Splicing in High-Risk Wilms' Tumors.International journal of molecular sciences · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Protein arginine methylation in transcription and epigenetic regulation.Frontiers in epigenetics and epigenomics · 2023
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Jian QinCentral laboratory, Renmin Hospital of Wuhan University, China.
Jian XuCenter for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA.ORCID 0000-0002-8162-889X
University of Southern California · USWuhan University · CN

Funding

Methylation signaling in periodontal health and diseaseR01DE026468 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI XU, JIAN · 2017 to 2021
$2.4M
Protein methylation pathways that control genetic susceptibility to environmental pollutants in the occurrence of craniofacial defectsR01DE030928 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI XU, JIAN · 2021 to 2025
$2.1M
Emotion Regulation and Sleep in Alcohol Use DisorderR21AA028617 · NIAAA · SRI INTERNATIONAL · PI BAKER, FIONA C, MULLER-OEHRING, EVA M · 2020 to 2021
$598k
Modulation of Runx2 activity by arginine methylationR21DE028617 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI XU, JIAN · 2019 to 2020
$454k
NIAAA NIH HHS R21 AA028617NIDCR NIH HHS R01 DE026468NIDCR NIH HHS R01 DE030928NIDCR NIH HHS R21 DE028617
6 · The paper itself

Abstract

Epithelial cells acquire mesenchymal characteristics during embryonic development, wound healing, fibrosis, and in cancer in a processed termed epithelial-to-mesenchymal transition (EMT). Regulatory networks of EMT are controlled by post-transcriptional, translational, and post-translational mechanisms, in which arginine methylation is critically involved. Here, we review arginine methylation-dependent mechanisms that regulate EMT in the aspects of signaling, transcriptional, and splicing regulation.

Indexed as

ArginineEpithelial-Mesenchymal TransitionArgininedifferentiationepithelial-mesenchymal transitionmethyltransferasePRMTprotein arginine methylation

Identifiers

PMID34358413
PMCPMC10181118
OpenAlexW3187268549

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.