Trial reportPloS one2021
Complementary treatment comparison for chronic pain management: A randomized longitudinal study.
Trial report in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Touch-based interventions, biofield therapies, and hypnosis for pain management: a scoping review of complementary approaches in physiotherapy.Frontiers in pain research (Lausanne, Switzerland) · 2026Pooled it
- [Cognitive-Behavioral therapy for patients with disability associated with chronic pain: systematic review of clinical trials]Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2025Pooled it
- Virtual Reality for Chronic Pain Management Among Historically Marginalized Populations: Systematic Review of Usability Studies.Journal of medical Internet research · 2023Pooled it
- Comparison of Experimental Pain Modulation by Hypnosis, Virtual Reality and Virtual Reality Hypnosis in Healthy Individuals.European journal of pain (London, England) · 2025Article
- The Use of Medical Hypnosis to Prevent and Treat Acute and Chronic Pain: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- Imbalances in the Content of Sleep and Pain Assessments in Patients with Chronic Pain: A Scoping Review.F1000Research · 2025Article
- Exploring Electrophysiological Responses to Hypnosis in Patients with Fibromyalgia.Brain sciences · 2024Article
- Adjunctive use of hypnosis for clinical pain: a systematic review and meta-analysis.Pain reports · 2024Review
- Mobile Health App and Web Platform (eDOL) for Medical Follow-Up of Patients With Chronic Pain: Cohort Study Involving the French eDOL National Cohort After 1 Year.JMIR mHealth and uHealth · 2024Article
- Practicing self-hypnosis to reduce chronic pain: A qualitative exploratory study of HYlaDO.British journal of pain · 2024Article
- Make me more comfortable: effects of a hypnosis session on pain perception in chronic pain patients.Frontiers in psychology · 2024Article
- Interventional pain blocks in Ontario: a population-based cross-sectional study on 2019 procedural volumes, clustering, and physician billings.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023Article
- Brain stimulation for chronic pain management: a narrative review of analgesic mechanisms and clinical evidence.Neurosurgical review · 2023Review
- Assessment and management of pain/nociception in patients with disorders of consciousness or locked-in syndrome: A narrative review.Frontiers in systems neuroscience · 2023Review
- Virtual reality hypnosis in the management of pain: Self-reported and neurophysiological measures in healthy subjects.European journal of pain (London, England) · 2023Article
- French Survey on Pain Perception and Management in Patients with Locked-In Syndrome.Diagnostics (Basel, Switzerland) · 2022Article
- Neuroimaging Mechanism of Cognitive Behavioral Therapy in Pain Management.Pain research & management · 2022Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn chronic pain, it seems that the effect of cognitive-behavioral therapy (CBT) is boosted when it is combined with hypnosis. The aim of this study was to assess the efficacy of self-hypnosis combined with self-care (i.e., a type of CBT) compared to music/self-care, self-care and psychoeducation/CBT and to evaluate their long-term effects.
methodsAn open label randomized clinical trial enrolled patients with chronic pain and was carried out at the University Hospital of Liège (Belgium). Patients were randomized into four groups: self-hypnosis/self-care, music/self-care, self-care, psychoeducation/CBT (7 monthly sessions of 2 hours). Two follow-up sessions were delivered at 6- and 12-month. Levels of pain, fatigue intensity, anxiety, depression, insomnia severity, disability, health locus of control, mental and physical quality of life and attitudes (control, disability, harm, emotion, medical cure, medication, solicitude) towards pain were assessed before and after the treatments, and at follow-up.
results203 patients were randomized: 52 in self-hypnosis/self-care, 59 in music/self-care, 47 in self-care, and 45 in psychoeducation/CBT. No group effect was found. A significant time effect was showed. Directly after the treatment, all groups decreased in pain attitudes and physical quality of life. Perceived control increased. At 6-month, all patients kept their levels of physical quality of life and perceived control, and showed decrease in pain intensity, harm, emotion and medical cure. At 12-month, scores that had change previously remained ameliorated, a decrease in insomnia severity and an increase in internal locus of control were observed.
conclusionsThe present findings are encouraging as they display long-term beneficial effects of complementary biopsychosocial-based treatments in chronic pain. It seems that patients continued to apply the learnt strategies as improvements were observed one year after the treatments had ended.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.