ArticleVaccines2021
Can Communication Strategies Combat COVID-19 Vaccine Hesitancy with Trade-Off between Public Service Messages and Public Skepticism? Experimental Evidence from Pakistan.
Article in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 4 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Communication-based interventions to increase COVID-19 vaccine willingness and uptake: a systematic review with meta-analysis.BMJ open · 2025Pooled it
- The Prevalence, Features, Influencing Factors, and Solutions for COVID-19 Vaccine Misinformation: Systematic Review.JMIR public health and surveillance · 2023Pooled it
- COVID-19 Vaccine Hesitancy in Pakistan: A Mini Review of the Published Discourse.Frontiers in public health · 2022Pooled it
- Systematic Review and Meta-Analysis of COVID-19 Vaccination Acceptance.Frontiers in medicine · 2021Pooled it
- Mapping risk communication practices in public health emergencies: a scoping review and comparison with Italian regional pandemic plans.BMC public health · 2026Article
- Message framing, identity congruence, and polio vaccine acceptance in Pakistan: Testing a social identity-based communication framework.Journal of virus eradication · 2026Article
- Conspiracy Beliefs, Institutional Mistrust, and Health-Related Behaviours During the COVID-19 Pandemic in Burkina Faso: A Mediation Analysis.The International journal of health planning and management · 2026Article
- Engaging the public with antimicrobial resistance through social media videos-a content analysis study.Frontiers in public health · 2026Article
- Exploring Implications of Risk Communication Strategies in Diminishing Adversities of Misinformation and Disinformation Against Hepatitis Vaccination in Global South.Risk management and healthcare policy · 2025Article
- Review
- Message Effectiveness of Fear Appeals in Vaccination Communication Campaigns: A Systematic Review.Vaccines · 2024Review
- A scoping review of COVID-19 vaccine hesitancy: refusal rate, associated factors, and strategies to reduce.Frontiers in public health · 2024Article
- Article
- Assessing How Risk Communication Surveillance Prompts COVID-19 Vaccine Acceptance Among Internet Users by Applying the Situational Theory of Problem Solving: Cross-Sectional Study.JMIR formative research · 2023Article
- Article
- Review
- Article
- Article
- COVID-19 vaccine-related misinformation identification among Chinese residents during a regional outbreak.Frontiers in public health · 2023Article
- COVID-19 vaccine communication and advocacy strategy: a social marketing campaign for increasing COVID-19 vaccine uptake in South Korea.Humanities & social sciences communications · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The COVID-19 pandemic may have reached a turning point as the World Health Organization and the global community of nations step up plans for mass vaccination campaigns. However, the COVID-19 vaccine-related conspiracy theories (e.g., falsehoods about birth control, women infertility, surveillance, and microchip humanity, etc.) have built new momentum for vaccine hesitancy. To this end, several nations worldwide, including Pakistan, are struggling to boost public trust and enthusiasm to get vaccinated, especially in an anxious and complicated atmosphere propelled by multiple, new and the deadliest variants of COVID-19. To address this critical research gap during these intensifying conditions of vaccine hesitancy, the present study makes the first attempt to explore the potential effects of various communication strategies, including public service message (safety benefits versus fear appraisals), media types (i.e., traditional versus digital), self-efficacy, perceived benefits and threats (susceptibility and severity), on the willingness to get vaccinated for COVID-19. Importantly, the underlying effects of public skepticism (in a moderating role) on these relationships were empirically examined. Using four fictitious COVID-19 immunization campaigns in a series of experiments with 2 (media type: traditional vs. digital) X 2 (service attribute: health and safety benefits vs. fear) message frames (represented as Group one to Group four), the findings identified fear appraisal as the most viable communication strategy in combating vaccine hesitancy. Moreover, public skepticism negatively moderated the effects of media types and public service message attributes on willingness to get vaccinated in relatively high (i.e., Group two), moderate (i.e., Group one and four), and low intensities (i.e., Group three). The pioneering findings of this research offer new strategic insights for the global health authorities and vaccine promoters to proactively address the downward spiral of people's willingness to take the COVID-19 vaccine.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.