Evidence map›Paper›PMID 34358061›Full record

ArticlePathogens (Basel, Switzerland)2021

Nationwide Seroprevalence of SARS-CoV-2 IgG Antibodies among Four Groups of Primary Health-Care Workers and Their Household Contacts 6 Months after the Initiation of the COVID-19 Vaccination Campaign in France: SeroPRIM Study Protocol.

Marie Pouquet, Dorine Decarreaux, Pol Prévot-Monsacré, Corentin Hervé, Andréas Werner, Brigitte Grosgogeat, Hélène Blanché, Pascaline Rabiega, Julien Laupie, Fabienne Kochert and 14 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04808986 (Séroprévalence Des IgG dirigés Contre le SARS-CoV-2 Chez Les Professionnels de santé en Soins Primaires et Leurs Contacts au Sein Des ménages), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04808986 nacompletednot on this map

Séroprévalence Des IgG dirigés Contre le SARS-CoV-2 Chez Les Professionnels de santé en Soins Primaires et Leurs Contacts au Sein Des ménages

TypeinterventionalSponsorInstitut National de la Santé Et de la Recherche Médicale, FranceRan2021 to 2021Enrolled2,817ConditionsCovid19ArmsSerological test for the detection of IgG anti-SARS-CoV-2
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 8 institutions in 1 country.

Marie PouquetINSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, (IPLESP), Sorbonne Université, 75012 Paris, France.
Dorine DecarreauxINSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, (IPLESP), Sorbonne Université, 75012 Paris, France.
Pol Prévot-MonsacréINSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, (IPLESP), Sorbonne Université, 75012 Paris, France.
Corentin HervéINSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, (IPLESP), Sorbonne Université, 75012 Paris, France.
Andréas WernerAssociation Française de Pédiatrie Ambulatoire (AFPA), 69000 Orléans, France.
Brigitte GrosgogeatFaculté d'Odontologie, Université Claude Bernard Lyon 1, Université de Lyon, 69000 Lyon, France.ORCID 0000-0003-2194-7300
Hélène BlanchéFondation Jean Dausset-CEPH, 75000 Paris, France.ORCID 0000-0003-2115-575X
Pascaline RabiegaIQVIA, Réseau de Pharmaciens, 75000 Paris, France.
Julien LaupieRéseau ReCOL, Association Dentaire Française, 75000 Paris, France.
Fabienne KochertAssociation Française de Pédiatrie Ambulatoire (AFPA), 69000 Orléans, France.
Nathalie AbrahamIQVIA, Réseau de Pharmaciens, 75000 Paris, France.
Jean-Marc SebaounFondation Jean Dausset-CEPH, 75000 Paris, France.
Xavier de LamballerieUnité des Virus Emergents, Aix Marseille University, IRD 190, INSERM U1207, 13005 Marseille, France.
Remi CharrelUnité des Virus Emergents, Aix Marseille University, IRD 190, INSERM U1207, 13005 Marseille, France.ORCID 0000-0002-7675-8251
Cecile SoutyINSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, (IPLESP), Sorbonne Université, 75012 Paris, France.
Ibrahima CamaraINSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, (IPLESP), Sorbonne Université, 75012 Paris, France.
Jeanne PergelineINSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, (IPLESP), Sorbonne Université, 75012 Paris, France.
Harold NoëlInfectious Diseases Division, Santé Publique France, 94410 Saint Maurice, France.
Caroline GuerrisiINSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, (IPLESP), Sorbonne Université, 75012 Paris, France.
Sylvie van der WerfUnit of Molecular Genetics of RNA Viruses, UMR 3569 CNRS, Institut Pasteur, University of Paris-Diderot, 75000 Paris, France.
Fabrice CarratINSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, (IPLESP), Sorbonne Université, 75012 Paris, France.
Thomas HanslikINSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, (IPLESP), Sorbonne Université, 75012 Paris, France.
Thierry BlanchonINSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, (IPLESP), Sorbonne Université, 75012 Paris, France.
Alessandra FalchiLaboratoire de Virologie, Université de Corse Pascal Paoli, UR7310 BioScope, 20250 Corte, France.ORCID 0000-0003-0799-1460
Inserm · FRAssociation Française de Pédiatrie Ambulatoire · FRFondation Jean Dausset-CEPH · FRIQVIA (France) · FRUniversité de Corse Pascal Paoli · FRCentre National de la Recherche Scientifique · FRSanté Publique France · FRUniversité Claude Bernard Lyon 1 · FR

Funding

Agence Nationale de la Recherche ANR-20-COV5-0005-01
6 · The paper itself

Abstract

backgroundThe protocol study will focus on the seroprevalence of IgG antibodies to SARS-CoV-2 achieved by vaccination and/or natural protection as well as the history, symptoms, and risk factors for SARS-CoV-2 in four primary health-care workers (PHCWs) and their household contacts in metropolitan France.

methodsHere, we propose a protocol for a nationwide survey to determine the seroprevalence of IgG antibodies to SARS-CoV-2 achieved by vaccination and/or natural protection in four PHCW populations (general practitioners, pediatricians, pharmacists and assistants, and dentists and assistants) and their household contacts. Participants will be included from June to July 2021 (Phase 1) among PHCW populations located throughout metropolitan France. They will be asked to provide a range of demographic and behavioral information since the first SARS-CoV-2 wave and a self-sampled dried blood spot. Phase 1 will involve also a questionnaire and serological study of PHCWs' household contacts. Seroprevalence will be estimated using two ELISAs designed to detect specific IgG antibodies to SARS-CoV-2 in humoral fluid, and these results will be confirmed using a virus neutralization test. This study will be repeated from November to December 2021 (Phase 2) to evaluate the evolution of immune status achieved by vaccination and/or natural protection of PHCWs and to describe the history of exposure to SARS-CoV-2.

Indexed as

householdprimary health-care workersSARS-CoV-2seroprevalencevaccination

Identifiers

PMID34358061
PMCPMC8308883
OpenAlexW3183779102

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.