Natural Infection of Dairy Cows with Bovine Leukemia Virus Affects Immunoglobulin Levels in Saliva and Serum but Not Milk.

Monika Dziuba, Vickie J Ruggiero, Catherine Wilson, Paul C Bartlett, Paul M Coussens

Open access · goldAbstract read

In one paragraph

Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.1field-weighted citation impact, top 60% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Monika DziubaCollege of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA.

Vickie J RuggieroCollege of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0003-3600-2027

Catherine WilsonDepartment of Animal Science, Michigan State University, Anthony Hall, 474 S. Shaw Lane, East Lansing, MI 48824, USA.

Paul C BartlettDepartment of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA.

Paul M CoussensDepartment of Animal Science, Michigan State University, Anthony Hall, 474 S. Shaw Lane, East Lansing, MI 48824, USA.

Michigan State University · US

Funding

U.S. Department of Agriculture 2014-67015-21632U.S. Department of Agriculture 2014-68004-21881

6 · The paper itself

Abstract

Bovine leukemia virus (BLV) is a retroviral infection that disrupts the immune function of infected animals. It is widespread among U.S. dairy cattle. In this pilot study, the average total IgA and IgM concentrations in milk, saliva, and serum samples from BLV ELISA-positive (ELISA+) dairy cows were compared against samples from BLV ELISA-negative (ELISA-) cows using the Kruskal-Wallis test (with ties). The results from ELISA+ cows were also stratified by lymphocyte count (LC) and proviral load (PVL). In milk and saliva from ELISA+ cows, the average total IgA and IgM concentrations were decreased compared to ELISA- cows, although this was only statistically significant for saliva IgM in cows with low PVL (

Indexed as

antibodyenzootic bovine leukosisimmunoglobulin Aimmunoglobulin Mlymphocytosisproviral load

Identifiers

PMID34358057

DOI10.3390/pathogens10070907

PMCPMC8308649

OpenAlexW3183705171

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.