Evidence map›Paper›PMID 34358028›Full record

ArticlePathogens (Basel, Switzerland)2021

Retrospective Study of the Seroprevalence of HIV, HCV, and HBV in Blood Donors at a Blood Bank of Western Mexico.

José de Jesús Guerrero-García, Alejandra Guadalupe Zúñiga-Magaña, Juan Carlos Barrera-De León, Rafael Magaña-Duarte, Daniel Ortuño-Sahagún

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. [Effectiveness of donor selection in a blood bank].Revista medica del Instituto Mexicano del Seguro Social · 2026
    Article
  2. [Screening of Hepatitis C virus in blood donors over 11 years].Revista medica del Instituto Mexicano del Seguro Social · 2026
    Observational
  3. Article
  4. Article
  5. Article
  6. Review
  7. [Blood donor infected VHB detected by NAT probable phase in clinical resolution].Revista medica del Instituto Mexicano del Seguro Social · 2024
    Article
  8. Article
  9. Seroprevalence of Transmisive Diseases in Healthy Blood Donors: a Five-year Experience in University Clinical Center Tuzla.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2023
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

José de Jesús Guerrero-GarcíaBanco de Sangre Central, UMAE Hospital de Especialidades CMNO, Instituto Mexicano del Seguro Social (IMSS), Guadalajara 44340, Jalisco, Mexico.ORCID 0000-0001-7039-6184
Alejandra Guadalupe Zúñiga-MagañaInstituto de Investigación en Ciencias Biomédicas (IICB), CUCS, Universidad de Guadalajara, Guadalajara 44340, Jalisco, Mexico.
Juan Carlos Barrera-De LeónCentro Médico Nacional de Occidente (CMNO), Unidad Médica de Alta Especialidad (UMAE), Hospital de Pediatría (HP), Instituto Mexicano del Seguro Social (IMSS), Guadalajara 44340, Jalisco, Mexico.
Rafael Magaña-DuarteBanco de Sangre Central, UMAE Hospital de Especialidades CMNO, Instituto Mexicano del Seguro Social (IMSS), Guadalajara 44340, Jalisco, Mexico.
Daniel Ortuño-SahagúnInstituto de Investigación en Ciencias Biomédicas (IICB), CUCS, Universidad de Guadalajara, Guadalajara 44340, Jalisco, Mexico.ORCID 0000-0002-7443-2514
Mexican Social Security Institute · MXUniversidad de Guadalajara · MX

Funding

Consejo Nacional de Ciencia y Tecnología CONACYT Ciencia de Frontera-2019-552265
6 · The paper itself

Abstract

Obtaining blood which is safe for transfusions is one of the principal challenges in the health systems of developing countries. Supply of contaminated blood increases morbidity, mortality, and the costs of patient care. In Mexico, serological screening is mandatory, but only a few of the main blood banks routinely perform a nucleic acid test (NAT). Data from 80,391 blood donations processed between August 2018 and December 2019 at the Central Blood Bank of the Western National Medical Center of the Mexican Social Security Institute (IMSS) were analyzed. All donors were screened for serological markers and NAT was performed. Reactive donors were followed-up to confirm their results. The number of reactive donors and seroprevalence rates for HIV, HCV, and HBV were 152 (18.91/10,000), 385 (47.89/10,000), and 181 (22.51/10,000), respectively; however, these rates decreased when NAT-confirmed reactive results were considered. Male donors were found to have a higher seroprevalence than females, and younger donors higher than older donors. The present study shows that HIV, HCV, and HBV seroprevalence in blood donors in Western Mexico is low. We propose that Mexico should establish future strategies, including pathogen reduction technologies (PRTs), in order to improve blood safety and reduce transfusion-transmissible infections (TTIs).

Indexed as

blood donorsMexicosafe bloodseroprevalenceTTIs

Identifiers

PMID34358028
PMCPMC8308904
OpenAlexW3182201140

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.