ArticlePathogens (Basel, Switzerland)2021
Histopathological Features of Symptomatic and Asymptomatic Honeybees Naturally Infected by Deformed Wing Virus.
Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 16 citations in OpenAlex.
- Larval Metabolic and Physiological Mechanisms Underlying Resistance to Chinese Sacbrood Virus inInsects · 2025Article
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- Effects of natural treatments on the varroa mite infestation levels and overall health of honey bee (Apis mellifera) colonies.PloS one · 2024Article
- Variants in the mitochondrial genome sequence of Oryctes rhinoceros (Coleoptera: Scarabaeidae) infected with Oryctes rhinoceros nudivirus in oil palm and coconut plantations.Scientific reports · 2023Article
- Co-Occurrence of Wing Deformity and Impaired Mobility of Alates with Deformed Wing Virus inInsects · 2023Article
- Prevalence ofMicroorganisms · 2023Article
- Essential Oils for a Sustainable Control of Honeybee Varroosis.Veterinary sciences · 2023Review
- Detection of honey bee viruses in larvae ofFrontiers in cellular and infection microbiology · 2023Article
- Special Issue: "Infection in Honey Bees: Host-Pathogen Interaction and Spillover".Pathogens (Basel, Switzerland) · 2022Article
- Detection of Honeybee Viruses inFrontiers in cellular and infection microbiology · 2022Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Deformed wing virus (DWV) is capable of infecting honeybees at every stage of development causing symptomatic and asymptomatic infections. To date, very little is known about the histopathological lesions caused by the virus. Therefore, 40 honeybee samples were randomly collected from a naturally DWV infected hive and subjected to anatomopathological examination to discriminate between symptomatic (29) and asymptomatic (11) honeybees. Subsequently, 15 honeybee samples were frozen at -80° and analyzed by PCR and RTqPCR to determinate the presence/absence of the virus and the relative viral load, while 25 honeybee samples were analyzed by histopathological techniques. Biomolecular results showed a fragment of the expected size (69bp) of DWV in all samples and the viral load was higher in symptomatic honeybees compared to the asymptomatic group. Histopathological results showed degenerative alterations of the hypopharyngeal glands (19/25) and flight muscles (6/25) in symptomatic samples while 4/25 asymptomatic samples showed an inflammatory response in the midgut and the hemocele. Results suggest a possible pathogenic action of DWV in both symptomatic and asymptomatic honeybees, and a role of the immune response in keeping under control the virus in asymptomatic individuals.
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