ArticlePathogens (Basel, Switzerland)2021
No Evidence for the Involvement of Leiomodin-1 Antibodies in the Pathogenesis of Onchocerciasis-Associated Epilepsy.
Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 25 citations in OpenAlex.
- Doxycycline for the treatment of nodding syndrome: a randomised, placebo-controlled, phase 2 trial.The Lancet. Global health · 2024Trial
- Onchocerciasis overview: pathogenesis, clinical spectrum, and therapeutic challenges of a neglected tropical disease.Frontiers in parasitology · 2026Review
- Investigating HLA haplotypes as a potential risk factor for nodding syndrome: A case-control study in the Mahenge area, Tanzania.PLoS neglected tropical diseases · 2025Article
- Prevalence of onchocerciasis and epilepsy in a Tanzanian region after a prolonged community-directed treatment with ivermectin.PLoS neglected tropical diseases · 2024Article
- Active infection with Onchocerca volvulus and the linkage to epilepsy/nodding syndrome.PLoS neglected tropical diseases · 2024Article
- Nodding syndrome is unlikely to be an autoimmune reaction to leiomodin-1 after infection byBiochemistry and biophysics reports · 2023Article
- Epilepsy and nodding syndrome in association with an Onchocerca volvulus infection drive distinct immune profile patterns.PLoS neglected tropical diseases · 2023Article
- The tau hypothesis of nodding syndrome in Africa.PLoS neglected tropical diseases · 2023Article
- Excitatory amino acids, possible causative agents of nodding syndrome in eastern Africa.Tropical medicine and health · 2023Article
- Comparison of Structural Changes in Nodding Syndrome and Other Epilepsies Associated WithNeurology(R) neuroimmunology & neuroinflammation · 2023Article
- The spectrum of disease and tau pathology of nodding syndrome in Uganda.Brain : a journal of neurology · 2023Article
- New clues to the elusive aetiology of nodding syndrome.Brain communications · 2023Article
- Parasitic, bacterial, viral, immune-mediated, metabolic and nutritional factors associated with nodding syndrome.Brain communications · 2023Article
- Nodding syndrome: A key role for sources of nutrition?eNeurologicalSci · 2022Review
- Neuroimmunology of Common Parasitic Infections in Africa.Frontiers in immunology · 2022Review
- Nodding Syndrome: A Scoping Review.Tropical medicine and infectious disease · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 3 countries.
Funding
Abstract
Nodding syndrome has been suggested to be triggered by neurotoxic leiomodin-1 auto-antibodies cross-reacting with
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.